Automated training for algorithms that learn from genomic data.
Automated training for algorithms that learn from genomic data.
复制标题
DOI:
10.1155/2015/234236
复制
发表时间:
2015
影响因子:
--
通讯作者:
Broschat SL
中科院分区:
文献类型:
--
作者:
Cilingir G;Broschat SL
Supervised machine learning algorithms are used by life scientists for a variety of objectives. Expert-curated public gene and protein databases are major resources for gathering data to train these algorithms. While these data resources are continuously updated, generally, these updates are not incorporated into published machine learning algorithms which thereby can become outdated soon after their introduction. In this paper, we propose a new model of operation for supervised machine learning algorithms that learn from genomic data. By defining these algorithms in a pipeline in which the training data gathering procedure and the learning process are automated, one can create a system that generates a classifier or predictor using information available from public resources. The proposed model is explained using three case studies on SignalP, MemLoci, and ApicoAP in which existing machine learning models are utilized in pipelines. Given that the vast majority of the procedures described for gathering training data can easily be automated, it is possible to transform valuable machine learning algorithms into self-evolving learners that benefit from the ever-changing data available for gene products and to develop new machine learning algorithms that are similarly capable.
登录
查看更多内容
影响因子:
14.9
作者:
Benson DA;Karsch-Mizrachi I;Lipman DJ;Ostell J;Sayers EW
通讯作者:
Sayers EW
DOI:
10.2307/2412448
发表时间:
1970-01-01
期刊:
SYSTEMATIC ZOOLOGY
影响因子:
--
作者:
FITCH, WM
通讯作者:
FITCH, WM
影响因子:
64.8
作者:
Fichera, ME;Roos, DS
通讯作者:
Roos, DS
影响因子:
3
作者:
Camacho C;Coulouris G;Avagyan V;Ma N;Papadopoulos J;Bealer K;Madden TL
通讯作者:
Madden TL
影响因子:
14.9
作者:
Aurrecoechea C;Brestelli J;Brunk BP;Fischer S;Gajria B;Gao X;Gingle A;Grant G;Harb OS;Heiges M;Innamorato F;Iodice J;Kissinger JC;Kraemer ET;Li W;Miller JA;Nayak V;Pennington C;Pinney DF;Roos DS;Ross C;Srinivasamoorthy G;Stoeckert CJ Jr;Thibodeau R;Treatman C;Wang H
通讯作者:
Wang H