Human infections with non-O157 Shiga toxin-producing Escherichia coli, Switzerland, 2000-2009.
Human infections with non-O157 Shiga toxin-producing Escherichia coli, Switzerland, 2000-2009.
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非O157志贺毒素产生的大肠杆菌的人类感染,瑞士,2000年至2009年。
DOI:
10.3201/eid1702.100909
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发表时间:
2011-02
影响因子:
11.8
通讯作者:
Stephan R
中科院分区:
文献类型:
--
作者:
Käppeli U;Hächler H;Giezendanner N;Beutin L;Stephan R
We characterized 97 non-O157 Shiga toxin (stx)–producing Escherichia coli strains isolated from human patients during 2000–2009 from the national reference laboratory in Switzerland. These strains belonged to 40 O:H serotypes; 4 serotypes (O26:H11/H–, O103:H2, O121:H19, and O145:H28/H–) accounted for 46.4% of the strains. Nonbloody diarrhea was reported by 23.2% of the patients, bloody diarrhea by 56.8%. Hemolytic uremic syndrome developed in 40.0% of patients; serotype O26:H11/H– was most often associated with this syndrome. Forty-five (46.4%) strains carried stx2 genes only, 36 strains (37.1%) carried stx1, and 16 (16.5%) strains carried stx1 and stx2. Genes encoding enterohemolysin and intimin were detected in 75.3% and 70.1% of the strains, respectively. Resistance to >1 antimicrobial agent was present in 25 isolates. High genetic diversity within strains indicates that non-O157 stx–producing E. coli infections in Switzerland most often occurred as single cases.
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影响因子:
9.4
作者:
Blanco, JE;Blanco, M;Blanco, J
通讯作者:
Blanco, J
影响因子:
9.4
作者:
Karmali, MA;Mascarenhas, M;Kaper, JB
通讯作者:
Kaper, JB
影响因子:
9.4
作者:
Bielaszewska, Martina;Stoewe, Franziska;Friedrich, Alexander W.
通讯作者:
Friedrich, Alexander W.
影响因子:
9.4
作者:
Boerlin, P;McEwen, SA;Gyles, CL
通讯作者:
Gyles, CL
影响因子:
14.2
作者:
Evans, J;Wilson, A;Smith, HR
通讯作者:
Smith, HR