A mild stress due to hypergravity exposure at youngage increases longevity in Drosophila melanogaster males
A mild stress due to hypergravity exposure at youngage increases longevity in Drosophila melanogaster males
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年轻时暴露于超重力环境造成的轻微压力可延长雄性果蝇的寿命
DOI：
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发表时间：
2004
期刊：
影响因子：
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通讯作者：
Philippe Bearet
中科院分区：
文献类型：
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作者：
É. Bourg;N. Minois;P. Bullens;Philippe Bearet
果蝇从两天大开始就暴露在超重力环境中，所用的重力水平范围为 2.58-7.38 g。暴露时间少于 14 天时，未观察到寿命变化。如果男性处于超重力状态14至24天，他们的寿命就会延长。这种寿命的延长从未在女性中观察到。两个实验室使用两种野生型菌株和不同的饲养条件复制了暴露于超重力环境的积极影响。短暂的超重力环境似乎是一种轻微的压力，对长寿产生积极影响。这与之前的两项研究一致，显示线虫和果蝇在热休克后寿命略有延长。
Drosophila melanogaster flies were exposed to hypergravity starting at two days of age, the range of gravity levels used being 2.58–7.38 g. No longevity change was observed for exposures of less than 14 days. The longevity of males increased if they were submitted to hypergravity for durations ranging from 14 to 24 days. This increase in longevity was never observed in females. The positive effect of exposure to hypergravity has been replicated in two laboratories using two wild-type strains and different rearing conditions. A short hypergravity exposure seems to be a mild stress, yielding positive effects on longevity. This is in accordance with two previous studies showing a slight longevity increase after heat shock in the nematode Caenorhabditis elegans and in Drosophila melanogaster.
DOI：
10.1093/gerona/52a.1.b48
发表时间：
1997-01-01
影响因子：
5.1
作者：
Khazaeli, AA;Tatar, M;Curtsinger, JW
通讯作者：
Curtsinger, JW
DOI：
10.1073/pnas.92.16.7540
发表时间：
1995-08-01
影响因子：
11.1
作者：
LITHGOW, GJ;WHITE, TM;JOHNSON, TE
通讯作者：
JOHNSON, TE
遗传变异和衰老。
影响因子：
11.1
作者：
Curtsinger,JW;Fukui,HH;Khazaeli,AA;Kirscher,A;Pletcher,SD;Promislow,DE;Tatar,M
通讯作者：
Tatar,M