Effect of oral functional training on immunological abilities of older people: a case control study.
Effect of oral functional training on immunological abilities of older people: a case control study.
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DOI：
10.1186/s12903-017-0461-7
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发表时间：
2018-01-08
期刊：
影响因子：
2.9
通讯作者：
Tsukinoki K
中科院分区：
文献类型：
--
作者：
Sato M;Sugimoto M;Yamamoto Y;Saruta J;Tsukinoki K
口腔功能能力随着年龄的增长而下降，全身免疫能力和生活质量也会下降。众所周知，老年人持续适度的全身运动可以改善口腔功能和免疫能力。在这里，我们评估了口腔运动作为无法进行全身运动的高龄老年人的替代训练方法的效果。在训练前收集了 3 次未刺激的全唾液样本作为基线数据，并在训练 3 周和 6 周后各收集了一次。指导参与者进行自我按摩；用舌头按压口轮匝肌和颊肌，并指示对三个主要腺体进行双边按摩以促进唾液分泌。还收集病史、日常生活习惯和特征。共有 30 名参与者（84.2±8.5 岁）入组。与之前的研究相反，没有观察到训练后唾液免疫球蛋白 A (IgA) 的增加。有趣的是，层次聚类分析揭示了明显的个体差异，即两个突出的聚类，以及刺激唾液流速和 IgA 流速之间的强正相关性，无论持续的口腔功能锻炼如何。在所有收集的参数中，只有体重指数（BMI）显示两组之间存在显着差异（Z = 2.06，P = 0.039，Wilcoxon 秩和检验）。口腔功能训练对高龄老年人唾液参数的影响有限。另一方面，体重指数比任何其他参数更能表征唾液特征，例如这些人是否患有疾病或服用药物。试验注册：2017年7月27日UMIN-CTR临床试验UMIN000028394，回顾性注册。
Oral functional ability decreases with age, and systemic immunological ability and quality of life can also deteriorate. Continuous moderate whole-body exercise for older people is known to improve oral functional and their immunological abilities. Here, we evaluated the effect of oral exercise as an alternative training method for highly older people who cannot perform whole-body exercises. Unstimulated whole saliva samples had been collected for three times before training as baseline data and one time after 3 and 6 weeks of training each. Participants were instructed to conduct self-massage; their tongues were used to press their orbicularis oris muscle and buccinators, and instructed to perform bilateral massage of three major glands for facilitating saliva secretion. Medical histories, daily life habits and characteristics were also collected. Totally 30 participants (84.2 ± 8.5 years) were enrolled. In contrast to previous researches, increase in salivary Immunoglobulin A (IgA) after the training was not observed. Interestingly, hierarchical clustering analyses revealed clear individual variations as two prominent clusters and a strong positive correlation between stimulated saliva flow rate and IgA flow rate, regardless of the continuous oral functional exercise. Only body mass index (BMI) showed significant differences between the two groups (Z = 2.06, P = 0.039, Wilcoxon rank-sum test) among all collected parameters. Oral functional training limitedly effects on salivary parameters of highly older people. On the other hand, BMI characterized salivary features more than any other parameters, such as the presence of diseases or medication use in these people. Trial registration: UMIN-CTR Clinical Trial UMIN000028394 on 27/July 2017, retrospectively registered.
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DOI：
10.1249/00005768-199307000-00011
发表时间：
1993-07-01
期刊：
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
影响因子：
--
作者：
NIEMAN, DC;HENSON, DA;NEHLSENCANNARELLA, SL
通讯作者：
NEHLSENCANNARELLA, SL
影响因子：
1.2
作者：
Takatsuji, Koichi;Sugimoto, Yoshie;Yamaguchi, Yukari
通讯作者：
Yamaguchi, Yukari
影响因子：
2
作者：
Ide, Momo;Saruta, Juri;Tsukinoki, Keiichi
通讯作者：
Tsukinoki, Keiichi
影响因子：
2.9
作者：
Soeda, R.;Tasaka, A.;Sakurai, K.
通讯作者：
Sakurai, K.
DOI：
10.1249/mss.0b013e318031306d
发表时间：
2007-04-01
期刊：
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
影响因子：
--
作者：
Shimizu, Kazuhiro;Kimura, Fuminori;Kono, Ichiro
通讯作者：
Kono, Ichiro