Visualized characterization for cerebral response of acupuncture deqi: paradox underway.
Visualized characterization for cerebral response of acupuncture deqi: paradox underway.
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DOI：
10.1155/2013/894750
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Liang FR
中科院分区：
文献类型：
--
作者：
Yang J;Yang MX;Zeng F;Wu X;Chen J;Liu YQ;Feng Y;Liang FR
针灸作为一种具有悠久历史的东方自然疗法，已被广泛应用于许多疾病的治疗。得气是著名的针刺针刺感觉，被认为是针刺疗效的预测指标，也是针刺取得较好疗效的前提。由于公认的证据不一致，至今对针刺得气的作用机制仍没有达成一致。近年来，利用现代技术对“得气”的可视化研究已经揭示了其可能的中枢机制，然而，针刺“得气”的脑反应研究存在着一个突出的悖论。本文综述了近年来利用功能磁共振成像（fMRI）和正电子发射断层扫描/计算机断层扫描（PET/CT）等可视化工具研究针刺“得气”脑反应的最新进展。从中医学的角度出发，突出了这一悖论的某些原因。据推测，穴位位于不同的皮肤部位，参与者的状态，和针刺操作都可以有助于目前的矛盾。因此，针刺得气的进一步研究应注意广义测量的实验设计策略，有效的假对照方法，以及更多的疾病状态下的受试者。
Acupuncture as an oriental natural healing therapy with prolonged history has been extensively utilized in the management of great numbers of disorders. Deqi, a renowned acupuncture needling sensation, is profoundly regarded as the predictor and also the prerequisite of a preferable acupuncture treatment efficacy. Till now, there is still no consistency being reached towards the mechanism of acupuncture Deqi as a result of the discrepancy for publicly acknowledged evidence. Recent visualized research on Deqi using modern technologies has demonstrated possible central mechanism towards it. However, there is a conspicuous paradox underway in the research of cerebral response to acupuncture Deqi. This paper provided a view of up-to-date studies using visualized tools to characterize the brain response to acupuncture Deqi, such as functional magnetic resonance imaging (fMRI) and positron emission tomography/computed tomography (PET/CT). The paradox was extruded to highlight certain reasons from a TCM view. It is hypothesized that acupoints located at different dermal sites, state of participant, and needling manipulation can all contribute to the current paradox. Hence, further studies on acupuncture Deqi should pay more attention to the strategy of experiment design with generalized measurement, valid sham control methods, and more to subjects in diseased condition.
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