Intense and Mild First Epidemic Wave of Coronavirus Disease, The Gambia.

Intense and Mild First Epidemic Wave of Coronavirus Disease, The Gambia.
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DOI:
10.3201/eid2708.204954
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发表时间:
2021-08
影响因子:
11.8
通讯作者:
Wariri O
Wariri O
中科院分区:
医学2区
文献类型:
--
作者:
Abatan B;Agboghoroma O;Akemoke F;Antonio M;Awokola B;Bittaye M;Bojang A;Bojang K;Brotherton H;Cerami C;Clarke E;D'Alessandro U;de Silva T;Drammeh M;Forrest K;Hofmann N;Jagne S;Jah H;Jarju S;Jaye A;Jobe M;Kampmann B;Manjang B;Martinez-Alvarez M;Mohammed N;Nadjm B;Ndiath MO;Nkereuwem E;Nwakanma D;Oko F;Okoh E;Okomo U;Olatunji Y;Oriero E;Prentice AM;Roberts C;Roca A;Sabally B;Sambou S;Samateh A;Secka O;Sesay AK;Singhateh Y;Susso B;Usuf E;Vilane A;Wariri O

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严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2) 大流行在非洲的演变与其他地区不同。非洲的 SARS-CoV-2 传播率较低,临床表现较温和。非洲需要详细的 SARS-CoV-2 流行病学数据。我们使用公开数据计算了冈比亚每 1,000 人的 SARS-CoV-2 感染率。我们评估了冈比亚医学研究理事会单位 (MRCG) 1,366 名员工的传播率,该单位对有症状病例进行了系统监测并进行了接触者追踪。截至 2020 年 9 月 30 日,冈比亚已发现 3,579 例 SARS-CoV-2 病例,其中 115 例死亡; 67% 的病例是在 8 月份发现的。感染者中,MRCG工作人员占191例;所有人都没有症状或症状轻微。非临床 MRCG 工作人员的累计发病率为 124 例感染/1,000 人,比人群中诊断病例估计值高出 80 倍以上。需要进行系统监测和血清流行病学调查来明确 SARS-CoV-2 在非洲的传播程度。
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is evolving differently in Africa than in other regions. Africa has lower SARS-CoV-2 transmission rates and milder clinical manifestations. Detailed SARS-CoV-2 epidemiologic data are needed in Africa. We used publicly available data to calculate SARS-CoV-2 infections per 1,000 persons in The Gambia. We evaluated transmission rates among 1,366 employees of the Medical Research Council Unit The Gambia (MRCG), where systematic surveillance of symptomatic cases and contact tracing were implemented. By September 30, 2020, The Gambia had identified 3,579 SARS-CoV-2 cases, including 115 deaths; 67% of cases were identified in August. Among infections, MRCG staff accounted for 191 cases; all were asymptomatic or mild. The cumulative incidence rate among nonclinical MRCG staff was 124 infections/1,000 persons, which is >80-fold higher than estimates of diagnosed cases among the population. Systematic surveillance and seroepidemiologic surveys are needed to clarify the extent of SARS-CoV-2 transmission in Africa.
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