The neurobiology of psychopathic traits in youths.
The neurobiology of psychopathic traits in youths.
复制标题
DOI：
10.1038/nrn3577
复制
发表时间：
2013-11
影响因子：
34.7
通讯作者：
Blair, R. James R.
中科院分区：
文献类型：
--
作者：
Blair, R. James R.
品行障碍是一种儿童行为障碍，其特征是持续的攻击性或反社会行为，破坏儿童的环境并损害其功能。一部分有品行障碍的孩子有精神病特征。精神病特征包括冷酷无情的成分和冲动反社会的成分，这与两个核心障碍有关。第一种是对他人痛苦的共情反应降低，这主要反映了杏仁核对痛苦线索的反应降低;第二种是决策和强化学习的缺陷，这反映了腹内侧前额叶皮层和纹状体的功能障碍。遗传和产前因素导致这些神经系统的异常发育，而影响动机的社会环境变量会影响随后表现出反社会行为的概率。
Conduct disorder is a childhood behaviour disorder that is characterized by persistent aggressive or antisocial behaviour that disrupts the child’s environment and impairs his or her functioning. A proportion of children with conduct disorder have psychopathic traits. Psychopathic traits consist of a callous–unemotional component and an impulsive–antisocial component, which are associated with two core impairments. The first is a reduced empathic response to the distress of other individuals, which primarily reflects reduced amygdala responsiveness to distress cues; the second is deficits in decision making and in reinforcement learning, which reflects dysfunction in the ventromedial prefrontal cortex and striatum. Genetic and prenatal factors contribute to the abnormal development of these neural systems, and social–environmental variables that affect motivation influence the probability that antisocial behaviour will be subsequently displayed.
登录
查看更多内容
影响因子：
5.6
作者：
Anastassiou-Hadjicharalambous, Xenia;Warden, David
通讯作者：
Warden, David
影响因子：
3.6
作者：
Blair, RJR;Colledge, E;Mitchell, DGV
通讯作者：
Mitchell, DGV
影响因子：
3.3
作者：
Aharoni, Eyal;Antonenko, Olga;Kiehl, Kent A.
通讯作者：
Kiehl, Kent A.
DOI：
10.1111/j.1469-7610.2009.02201.x
发表时间：
2010-07
期刊：
Journal of child psychology and psychiatry, and allied disciplines
影响因子：
--
作者：
Bjork JM;Chen G;Smith AR;Hommer DW
通讯作者：
Hommer DW
影响因子：
64.8
作者：
Adolphs, R;Gosselin, F;Damasio, AR
通讯作者：
Damasio, AR