Enhancing preparation for large Nipah outbreaks beyond Bangladesh: Preventing a tragedy like Ebola in West Africa.
Enhancing preparation for large Nipah outbreaks beyond Bangladesh: Preventing a tragedy like Ebola in West Africa.
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DOI：
10.1016/j.ijid.2018.05.015
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发表时间：
2018-07
期刊：
影响因子：
--
通讯作者：
Lucey D
中科院分区：
文献类型：
--
作者：
Donaldson H;Lucey D
尼帕病毒的流行病学在马来西亚、孟加拉国和菲律宾各不相同。在孟加拉国以外，需要加强对尼帕病毒大规模爆发的准备。应该防止尼帕病毒在南亚以外的地区流行，以避免像西非埃博拉病毒那样的悲剧。尼帕病毒在印度（包括2018年5月的喀拉拉邦）、孟加拉国和菲律宾的非城市地区通过密切接触在人与人之间传播。它可引起脑炎和肺炎，病死率高。尼帕是一种与果蝠有关的人畜共患传染病，有时也与猪或马有关。我们提倡预测和准备城市和更大的农村尼帕疫情。立即加强的准备工作将包括世界卫生组织（WHO）在其OpenWHO网站和2018年《流行病管理》手册上提供的关于感染预防和控制的标准化指导以及个人防护设备，沿着孟加拉国和印度等多次爆发国家的专家的最佳临床实践。更长期的强化准备包括加速开发现场诊断、抗病毒药物、免疫疗法和疫苗。需要世卫组织协调的多伙伴协议来测试研究性治疗、诊断和疫苗，类似于在几内亚、利比里亚和塞拉利昂发生意想不到的大流行期间针对埃博拉病毒的此类协议。在没有尼帕经验的国家，现在就预测和准备城市和农村的尼帕疫情将有助于避免联合国2016年关于西非埃博拉病毒的报告所称的“可预防的悲剧”。
Nipah epidemiology has differed in Malaysia, Bangladesh, and the Philippines. Beyond Bangladesh, there is a need to enhance preparedness for large Nipah outbreaks. Nipah epidemics beyond South Asia should be prevented to avoid a tragedy like Ebola in West Africa. The Nipah virus has been transmitted from person-to-person via close contact in non-urban parts of India (including Kerala May 2018), Bangladesh, and the Philippines. It can cause encephalitis and pneumonia, and has a high case fatality rate. Nipah is a One Health zoonotic infectious disease linked to fruit bats, and sometimes pigs or horses. We advocate anticipating and preparing for urban and larger rural outbreaks of Nipah. Immediate enhanced preparations would include standardized guidance on infection prevention and control, and personal protective equipment, from the World Health Organization (WHO) on their OpenWHO website and 2018 “Managing Epidemics” handbook, along with adding best clinical practices by experts in countries with multiple outbreaks such as Bangladesh and India. Longer-term enhanced preparations include accelerating development of field diagnostics, antiviral drugs, immune-based therapies, and vaccines. WHO-coordinated multi-partner protocols to test investigational treatments, diagnostics, and vaccines are needed, by analogy to such protocols for Ebola during the unanticipated pan-epidemic in Guinea, Liberia, and Sierra Leone. Anticipating and preparing now for urban and rural Nipah outbreaks in nations with no experience with Nipah will help avoid the potential for what the United Nations 2016 report on Ebola in West Africa called a “preventable tragedy”.
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影响因子：
7.6
作者：
Luby, Stephen P.
通讯作者：
Luby, Stephen P.
影响因子：
11.8
作者：
Luby SP;Hossain MJ;Gurley ES;Ahmed BN;Banu S;Khan SU;Homaira N;Rota PA;Rollin PE;Comer JA;Kenah E;Ksiazek TG;Rahman M
通讯作者：
Rahman M
DOI：
10.1098/rsif.2011.0223
发表时间：
2012-01-07
期刊：
Journal of the Royal Society, Interface
影响因子：
--
作者：
Pulliam JR;Epstein JH;Dushoff J;Rahman SA;Bunning M;Jamaluddin AA;Hyatt AD;Field HE;Dobson AP;Daszak P;Henipavirus Ecology Research Group (HERG)
通讯作者：
Henipavirus Ecology Research Group (HERG)
影响因子：
11.8
作者：
Arankalle VA;Bandyopadhyay BT;Ramdasi AY;Jadi R;Patil DR;Rahman M;Majumdar M;Banerjee PS;Hati AK;Goswami RP;Neogi DK;Mishra AC
通讯作者：
Mishra AC
影响因子：
3.3
作者：
Hahn, Micah B.;Gurley, Emily S.;Luby, Stephen P.
通讯作者：
Luby, Stephen P.