Schistosoma mansoni Infection Is Associated With Increased Monocytes and Fewer Natural Killer T Cells in the Female Genital Tract.

Schistosoma mansoni Infection Is Associated With Increased Monocytes and Fewer Natural Killer T Cells in the Female Genital Tract.
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DOI:
10.1093/ofid/ofac657
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发表时间:
2022-12
影响因子:
4.2
通讯作者:
--
中科院分区:
医学3区
文献类型:
--
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曼氏血吸虫感染可能会损害生殖器粘膜的抗病毒免疫,但免疫细胞群尚未得到很好的表征。我们鉴定了患有和不患有S曼氏吸虫感染的妇女宫颈刷子中的单个核细胞。我们观察到感染女性的自然杀伤T细胞频率较低,CD14+单核细胞频率较高。
Schistosoma mansoni infection may impair genital mucosal antiviral immunity, but immune cell populations have not been well characterized. We characterized mononuclear cells from cervical brushings of women with and without S mansoni infection. We observed lower frequencies of natural killer T cells and higher frequencies of CD14+ monocytes in infected women.
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