Design of portable mass spectrometers with handheld probes: aspects of the sampling and miniature pumping systems.
Design of portable mass spectrometers with handheld probes: aspects of the sampling and miniature pumping systems.
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DOI：
10.1007/s13361-014-1026-5
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发表时间：
2015-02
影响因子：
3.2
通讯作者：
Ouyang Z
中科院分区：
文献类型：
--
作者：
Chen CH;Chen TC;Zhou X;Kline-Schoder R;Sorensen P;Cooks RG;Ouyang Z
配有取样探头的背包结构的微型质谱仪分析系统可能对现场实时化学分析具有重要意义。在这项研究中，探索了不同的配置，其中使用一个细长的管子来连接用于产生和保持真空的涡轮增压泵和后备泵。此外，我们还首次推出了两种用于微型质谱计的新型泵--Creare 130G阻力泵和Creare 350G涡旋泵。这些泵以及另一台Creare 550涡轮增压泵以及市面上可买到的Pfeiffer HiPace 10涡轮增压泵和KNF隔膜后备泵，都在背包配置下进行了测试。采用非连续大气压界面(DAPI)进行离子导入，对系统性能，特别是扫描时间进行了表征。在1mtorr以上的压力区内的泵送性能对DAPI的运行至关重要。550G涡轮增压泵被证明具有相对更高的泵速，超过1mtorr，扫描时间为300ms，几乎是通常与微型质谱仪一起使用的更大、更重的HiPace 10所获得的值的一半。350g涡旋泵也被发现是对通常用作后备泵的隔膜泵的改进。用同轴低温等离子体离子源直接分析低挥发性化合物玻片，包括1 ng 2，4-二硝基苯酚和10 ng TNT(2，4，6-三硝基甲苯)，用Creare 550g涡轮泵，以及10 ng可卡因和20 ng DNP，用Creare 130g拖拉泵。
Miniature mass spectrometry analytical systems of backpack configuration fitted with sampling probes could potentially be of significant interest for in-field, real-time chemical analysis. In this study, various configurations were explored in which a long narrow tube was used to connect the turbo and backing pumps used to create and maintain vacuum. Also, for the first time we introduced two new types of pumps for miniature mass spectrometers, the Creare 130g drag pump and Creare 350g scroll backing pump. These pumps, along with another Creare 550 turbo pump and the commercially available Pfeiffer HiPace 10 turbo and KnF diaphragm backing pumps, were tested with the backpack configurations. The system performance, especially the scan time, was characterized when used with a discontinuous atmospheric pressure interface (DAPI) for ion introduction. The pumping performance in the pressure region above 1 mtorr is critical for DAPI operation. The 550g turbo pump was shown to have a relatively higher pumping speed above 1 mtorr and gave a scan time of 300 ms, almost half the value obtained with the larger, heavier HiPace 10 often used with miniature mass spectrometers. The 350 g scroll pump was also found to be an improvement over the diaphragm pumps generally used as backing pumps. With a coaxial low temperature plasma ion source, direct analysis of low volatility compounds glass slides was demonstrated, including 1 ng DNP (2,4-Dinitrophenol) and 10ng TNT (2,4,6-trinitrotoluene) with Creare 550g turbo pump as well as 10 ng cocaine and 20 ng DNP with Creare 130g drag pump.
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影响因子：
2
作者：
Dalgleish, Jon K.;Hou, Keyong;Cooks, R. Graham
通讯作者：
Cooks, R. Graham
影响因子：
7.4
作者：
Gao, Liang;Song, Qingyu;Ouyang, Zheng
通讯作者：
Ouyang, Zheng
影响因子：
2
作者：
He, Jiuming;Tang, Fei;Abliz, Zeper
通讯作者：
Abliz, Zeper
影响因子：
4.9
作者：
Justes, Dina R.;Talaty, Nari;Cooks, R. Graham
通讯作者：
Cooks, R. Graham
影响因子：
7.4
作者：
Garcia-Reyes, Juan F.;Harper, Jason D.;Cooks, R. Graham
通讯作者：
Cooks, R. Graham