Widespread multiple insecticide resistance in the major dengue vector Aedes albopictus in Hainan Province, China.
Widespread multiple insecticide resistance in the major dengue vector Aedes albopictus in Hainan Province, China.
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中国海南省主要登革热媒介白纹伊蚊普遍存在多种杀虫剂抗药性。
DOI：
10.1002/ps.6222
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发表时间：
2021-04
影响因子：
4.1
通讯作者：
Yan G
中科院分区：
文献类型：
--
作者：
Li Y;Zhou G;Zhong D;Wang X;Hemming-Schroeder E;David RE;Lee MC;Zhong S;Yi G;Liu Z;Cui G;Yan G
白纹伊蚊是一种高度侵入性的蚊子，已成为登革热、基孔肯雅和寨卡病毒的潜在传播媒介。基于杀虫剂的蚊虫干预措施是控制病媒传播疾病的主要工具。然而，蚊子对杀虫剂的抗药性是有效预防和控制的主要威胁。五Ae.调查了海南省白纹伊蚊种群对多种杀虫剂的敏感性及抗性机制。幼虫生物测定表明，所有幼虫种群对拟除虫菊酯的抗性是普遍的。成人生物测定显示，所有人口的抗性或高度耐至少四个六种合成杀虫剂（溴氰菊酯，二氯苯醚菊酯，氟氯氰菊酯，残杀威，马拉硫磷，滴滴涕）测试。在DDT、马拉硫磷和氯菊酯的生物测定中，蚊子预先暴露于增效剂增效醚（PBO）使蚊子死亡率增加2.4-43.3%，并使蚊子对溴氰菊酯、氟氯氰菊酯和残杀威敏感。在田间抗性群体和敏感群体中，敲低抗性（kdr）突变（F1534 S和F1534 C）的频率范围分别为69.8%-89.3%和38.1%-87.0%。F1534 S突变与拟除虫菊酯抗性显著相关。在两个受检人群中未检测到乙酰胆碱酯酶（ace-1）基因突变。这项研究提供了证据，广泛的抗性多种杀虫剂在Ae。白纹伊蚊在海南省的分布。kdr基因突变和代谢解毒作用是Ae产生抗药性的潜在原因。白纹伊蚊我们的研究结果强调了杀虫剂耐药性管理和蚊子控制措施的必要性，这些措施不完全依赖于合成杀虫剂。版权所有2020作者。有害生物管理科学由John Wiley & Sons Ltd代表化学工业协会出版。世卫组织标准杀虫剂敏感性测试发现，中国海南省主要登革热病媒白纹伊蚊对多种杀虫剂产生抗药性。版权所有2020作者。《害虫管理科学》由John Wiley & Sons Ltd代表化学工业协会出版。
Aedes albopictus is a highly invasive mosquito and has become a potential vector of dengue, chikungunya and Zika viruses. Insecticide‐based mosquito interventions are the main tools for vector‐borne disease control. However, mosquito resistance to insecticides is a major threat to effective prevention and control. Five Ae. albopictus populations across Hainan Province, China were investigated for susceptibility to multiple insecticide and resistance mechanisms. Larval bioassays indicated that resistance to pyrethroids was common in all larval populations. Adult bioassays revealed all populations were either resistant or highly resistant to at least four of the six synthetic insecticides (deltamethrin, permethrin, cyfluthrin, propoxur, malathion, and DDT) tested. Pre‐exposure of mosquitoes to the synergistic agent piperonyl butoxide (PBO) increased mosquito mortality by 2.4–43.3% in bioassays to DDT, malathion, and permethrin and rendered mosquito sensitive to deltamethrin, cyfluthrin, and propoxur. The frequency of knockdown resistance (kdr) mutations (F1534S and F1534C) ranged from 69.8% to 89.3% and from 38.1% to 87.0% in field‐resistant and sensitive populations, respectively. F1534S mutation was significantly associated with pyrethroid resistance. No mutation was detected in the acetylcholinesterase (ace‐1) gene in the two examined populations. This study provides evidence of widespread resistance to multiple insecticides in Ae. albopictus in Hainan Province, China. Both kdr mutations and metabolic detoxification were potential causes of insecticide resistance for Ae. albopictus. Our findings highlight the need for insecticide resistance management and mosquito control measures that do not entirely depend on synthetic insecticides. © 2020 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry. WHO standard insecticide susceptibility tests found multiple insecticide resistance in major dengue vector Aedes albopictus across Hainan Province, China. © 2020 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
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影响因子：
3
作者：
Dadzie SK;Chabi J;Asafu-Adjaye A;Owusu-Akrofi O;Baffoe-Wilmot A;Malm K;Bart-Plange C;Coleman S;Appawu MA;Boakye DA
通讯作者：
Boakye DA
影响因子：
3.2
作者：
Fang, Yuan;Shi, Wen-Qi;Zhang, Yi
通讯作者：
Zhang, Yi
影响因子：
9.6
作者：
Bonizzoni M;Gasperi G;Chen X;James AA
通讯作者：
James AA
DOI：
10.2471/blt.09.067892
发表时间：
2010-03-01
期刊：
Bulletin of the World Health Organization: International Journal of Public Health
影响因子：
--
作者：
Arunachalam, Natarajan;Tana, Susilowati;Petzold, Max
通讯作者：
Petzold, Max
影响因子：
3.8
作者：
Grisales N;Poupardin R;Gomez S;Fonseca-Gonzalez I;Ranson H;Lenhart A
通讯作者：
Lenhart A