Individual differences in impulsivity predict head motion during magnetic resonance imaging.

Individual differences in impulsivity predict head motion during magnetic resonance imaging.
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冲动的个体差异预测磁共振成像期间的头部运动

DOI:
10.1371/journal.pone.0104989
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发表时间:
2014
期刊:
影响因子:
3.7
通讯作者:
Liu J
Liu J
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Kong XZ;Zhen Z;Li X;Lu HH;Wang R;Liu L;He Y;Zang Y;Liu J

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磁共振成像(MRI)提供了有价值的数据,了解人类的思想和大脑疾病,但在扫描仪头部运动引入系统和虚假的偏见。例如,MRI测量的差异(例如,网络强度、白色物质完整性)可能是由于他们头部运动的差异。为了确定头部运动本身是否是一个重要的变量,或者仅仅是一个混淆变量,我们探索了心理特征的个体差异,这些心理特征可能使一些人在MRI扫描期间比其他人移动更多。在前两项研究中,我们在儿童(N = 245)和成人(N = 581)中证明,通过静息态功能MRI和弥散张量成像估计的头部运动与冲动评分可靠相关。    此外,注意缺陷多动障碍(ADHD)儿童和正常发育儿童之间头部运动的差异主要是由于冲动性的差异。最后,在第三项研究中,我们证实了这样的观察结果,即回归方法,旨在通过在组分析中回归运动来处理运动问题,会低估兴趣的影响。总之,目前的研究结果提供了经验证据,链接在扫描仪头部运动的心理特征。
Magnetic resonance imaging (MRI) provides valuable data for understanding the human mind and brain disorders, but in-scanner head motion introduces systematic and spurious biases. For example, differences in MRI measures (e.g., network strength, white matter integrity) between patient and control groups may be due to the differences in their head motion. To determine whether head motion is an important variable in itself, or just simply a confounding variable, we explored individual differences in psychological traits that may predispose some people to move more than others during an MRI scan. In the first two studies, we demonstrated in both children (N  =  245) and adults (N  =  581) that head motion, estimated from resting-state functional MRI and diffusion tensor imaging, was reliably correlated with impulsivity scores. Further, the difference in head motion between children with attention deficit hyperactivity disorder (ADHD) and typically developing children was largely due to differences in impulsivity. Finally, in the third study, we confirmed the observation that the regression approach, which aims to deal with motion issues by regressing out motion in the group analysis, would underestimate the effect of interest. Taken together, the present findings provide empirical evidence that links in-scanner head motion to psychological traits.
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