Identifying sources of tick blood meals using unidentified tandem mass spectral libraries.
Identifying sources of tick blood meals using unidentified tandem mass spectral libraries.
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DOI：
10.1038/ncomms2730
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发表时间：
2013
影响因子：
16.6
通讯作者：
中科院分区：
文献类型：
--
作者：
Rapid and reliable identification of the vertebrate species on which a disease vector previously parasitized is imperative to study ecological factors that affect pathogen distribution and can aid the development of public health programs. Here we describe a proteome profiling technique designed to identify the source of blood meals of hematophagous arthropods. This method employs direct spectral matching and thus does not require a priori knowledge of any genetic or protein sequence information. Using this technology, we detect remnants of blood in blacklegged ticks (Ixodes scapularis) and correctly determine the vertebrate species from which the blood was derived even six months after the tick had fed. This biological fingerprinting methodology is sensitive, fast, cost-effective, and can potentially be adapted for other biological and medical applications when existing genome-based methods are impractical or ineffective.
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影响因子：
3.4
作者：
Deutsch, Eric W.;Mendoza, Luis;Shteynberg, David;Farrah, Terry;Lam, Henry;Tasman, Natalie;Sun, Zhi;Nilsson, Erik;Pratt, Brian;Prazen, Bryan;Eng, Jimmy K.;Martin, Daniel B.;Nesvizhskii, Alexey I.;Aebersold, Ruedi
通讯作者：
Aebersold, Ruedi
影响因子：
4.4
作者：
Dasari, Surendra;Chambers, Matthew C.;Tabb, David L.
通讯作者：
Tabb, David L.
影响因子：
64.8
作者：
Keesing F;Belden LK;Daszak P;Dobson A;Harvell CD;Holt RD;Hudson P;Jolles A;Jones KE;Mitchell CE;Myers SS;Bogich T;Ostfeld RS
通讯作者：
Ostfeld RS
DOI：
10.4269/ajtmh.1981.30.1336
发表时间：
1981-01-01
影响因子：
3.3
作者：
BURKOT, TR;GOODMAN, WG;DEFOLIART, GR
通讯作者：
DEFOLIART, GR
影响因子：
12.7
作者：
GLASS, GE;SCHWARTZ, BS;ISRAEL, E
通讯作者：
ISRAEL, E