Calcium Deficiency in Bangladesh: Burden and Proposed Solutions for the First 1000 Days.
Calcium Deficiency in Bangladesh: Burden and Proposed Solutions for the First 1000 Days.
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DOI：
10.1177/0379572116652748
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发表时间：
2016-12
影响因子：
1.9
通讯作者：
Fawzi WW
中科院分区：
文献类型：
--
作者：
Bromage S;Ahmed T;Fawzi WW
孟加拉国是世界上发育迟缓和微量营养素缺乏症发病率最高的国家之一，尽管在过去35年里，孟加拉国努力防治疟疾、呼吸道感染和蛋白质能量营养不良，使儿童死亡率持续大幅下降。虽然项目通常更加关注其他微量营养素，但钙对健康的重要性在当地却没有得到充分的认识。综合有关孟加拉国钙缺乏症的现有信息，以便为有效的国家钙计划的设计提供信息。我们检索了3个在线数据库和大量调查报告，对孟加拉国的钙流行病学进行了叙述性审查，包括人口摄入量，缺乏的决定因素和后果，并测试了干预措施，特别是幼儿和育龄妇女。此外，还对全国住户调查进行了二次分析，以确定不同人口中钙充足的相对程度。孟加拉国一般人口的钙摄入量很低，对公众健康可能产生严重和持久的影响。这些影响尤其与幼儿和育龄妇女有关，因为这些群体的生理需求增加，膳食钙来源不成比例地少，以及其他当地钙状况决定因素的综合作用。孕妇的片剂补充计划是减少先兆子痫和早产的一种有吸引力的方法。进一步的研究是必要的，以解决不同的有前途的方法在儿童预防佝偻病的比较效益。
Bangladesh incurs among the highest prevalence of stunting and micronutrient deficiencies in the world, despite efforts against diarrheal disease, respiratory infections, and protein energy malnutrition which have led to substantial and continuous reductions in child mortality over the past 35 years. Although programs have generally paid more attention to other micronutrients, the local importance of calcium to health has been less recognized. To synthesize available information on calcium deficiency in Bangladesh in order to inform the design of an effective national calcium program. We searched 3 online databases and a multitude of survey reports to conduct a narrative review of calcium epidemiology in Bangladesh, including population intake, determinants and consequences of deficiency, and tested interventions, with particular reference to young children and women of childbearing age. This was supplemented with secondary analysis of a national household survey in order to map the relative extent of calcium adequacy among different demographics. Intake of calcium is low in the general population of Bangladesh, with potentially serious and persistent effects on public health. These effects are especially pertinent to young children and reproductive-age women, by virtue of increased physiologic needs, disproportionately poor access to dietary calcium sources, and a confluence of other local determinants of calcium status in these groups. A tablet supplementation program for pregnant women is an appealing approach for the reduction in preeclampsia and preterm birth. Further research is warranted to address the comparative benefit of different promising approaches in children for the prevention of rickets.
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影响因子：
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