Insomnia and its impact on physical and mental health.
Insomnia and its impact on physical and mental health.
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DOI：
10.1007/s11920-013-0418-8
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发表时间：
2013-12
影响因子：
6.7
通讯作者：
Vgontzas, Alexandros N.
中科院分区：
文献类型：
--
作者：
Fernandez-Mendoza, Julio;Vgontzas, Alexandros N.
关键词：
与失眠与心理健康的关系相反，它与身体健康的关系直到最近才得到很大程度的探索。基于客观睡眠时间短的失眠与应激系统的四肢激活和其他生理过度觉醒指标相关的研究结果，这应该对身心健康产生不利影响，我们最近证明这种失眠表型与心脏代谢和神经认知发病率和死亡率的显著风险相关。相反，睡眠时间正常的失眠症与睡眠错觉和认知情绪觉醒有关，但与生理过度觉醒或心脏代谢或神经认知疾病的迹象无关。有趣的是，两种失眠表型都与心理健康有关，尽管很可能是通过不同的病理生理机制。我们建议，客观测量睡眠时间可能成为失眠常规评估和诊断的一部分，这两种失眠表型可能对生物治疗和心理治疗有不同的反应。
In contrast to the association of insomnia with mental health, its association with physical health has remained largely unexplored until recently. Based on findings that insomnia with objective short sleep duration is associated with activation of both limbs of the stress system and other indices of physiological hyperarousal, which should affect adversely physical and mental health, we have recently demonstrated that this insomnia phenotype is associated with a significant risk of cardiometabolic and neurocognitive morbidity and mortality. In contrast, insomnia with normal sleep duration is associated with sleep misperception and cognitive-emotional arousal but not with signs of physiological hyperarousal or cardiometabolic or neurocognitive morbidity. Interestingly, both insomnia phenotypes are associated with mental health, although most likely through different pathophysiological mechanisms. We propose that objective measures of sleep duration may become part of the routine evaluation and diagnosis of insomnia and that these two insomnia phenotypes may respond differentially to biological vs. psychological treatments.
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影响因子：
120.7
作者：
Edinger, JD;Wohlgemuth, WK;Quillian, RE
通讯作者：
Quillian, RE
DOI：
10.1523/jneurosci.1809-08.2008
发表时间：
2008-10-01
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Cano G;Mochizuki T;Saper CB
通讯作者：
Saper CB
影响因子：
5.6
作者：
Corsi-Cabrera, Maria;Figueredo-Rodriguez, Pedro;Bosch-Bayard, Jorge
通讯作者：
Bosch-Bayard, Jorge
影响因子：
3.3
作者：
Fernandez-Mendoza, Julio;Vela-Bueno, Antonio;Jose De la Cruz-Troca, Juan
通讯作者：
Jose De la Cruz-Troca, Juan
影响因子：
5.6
作者：
BONNET, MH;ARAND, DL
通讯作者：
ARAND, DL