A novel electrospinning target to improve the yield of uniaxially aligned fibers.
A novel electrospinning target to improve the yield of uniaxially aligned fibers.
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DOI：
10.1002/btpr.163
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发表时间：
2009-07
影响因子：
2.9
通讯作者：
Wang Y
中科院分区：
文献类型：
--
作者：
Secasanu VP;Giardina CK;Wang Y
静电纺丝是一种有用的技术，可以产生微纳米尺寸的纤维。修改静电纺丝参数，如沉积目标几何形状，可以产生单轴排列的纤维，用于从组织工程到材料制造的各种应用。例如，纤维网已被证明可以模拟细胞外基质网络，用于平滑肌细胞增殖。此外，排列的纤维可以引导神经突沿着纤维的方向生长。在这里，我们提出了一种新的电纺丝沉积靶，它结合了先前报道的两种电极的优点：标准平行电极和具有锐边的纺丝轮。这种新的靶设计显著提高了定向光纤产量。具体来说，目标由两个平行的铝板组成，边缘锋利，分岔角为26°。电场计算表明，电场矢量排列的可能面积较大。与现有的平行电极相比，这种新的沉积目标允许纤维沉积在更大的横截面积上，并且至少使单轴排列纤维的产量增加一倍。此外，从沉积目标收集后，纤维的排列和形态被保留。
Electrospinning is a useful technique that can generate micro- and nano-meter sized fibers. Modification of the electrospinning parameters, such as deposition target geometry, can generate uniaxially aligned fibers for use in diverse applications ranging from tissue engineering to material fabrication. For example, meshes of fibers have been shown to mimic the extracellular matrix networks for use in smooth muscle cell proliferation. Further, aligned fibers can guide neurites to grow along the direction of the fibers. Here we present a novel electrospinning deposition target that combines the benefits of two previously reported electrodes: the standard parallel electrodes and the spinning wheel with a sharpened edge. This new target design significantly improves aligned fiber yield. Specifically, the target consists of two parallel aluminum plates with sharpened edges containing a bifurcating angle of 26°. Electric field computations show a larger probable area of aligned electric field vectors. This new deposition target allows fibers to deposit on a larger cross-sectional area relative to the existing parallel electrode and at least doubles the yield of uniaxially aligned fibers. Further, fiber alignment and morphology are preserved after collection from the deposition target.
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