Type I interferon response to extracellular bacteria in the airway epithelium.
Type I interferon response to extracellular bacteria in the airway epithelium.
复制标题
I型干扰素对气道上皮细胞外细菌的反应。
DOI：
10.1016/j.it.2011.09.003
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发表时间：
2011-12
影响因子：
16.8
通讯作者：
Prince A
中科院分区：
文献类型：
--
作者：
Parker D;Prince A
The airway epithelium possesses many mechanisms to prevent bacterial infection. Not only does it provide a physical barrier but it also acts as an extension of the immune system through the expression of innate immune receptors and corresponding effectors. One outcome of innate signaling by the epithelium is the production of type I interferons (IFN) , which have traditionally been associated with activation via viral and intracellular organisms. We discuss how three extracellular bacterial pathogens of the airway activate this intracellular signaling cascade through both surface components as well as via secretion systems and the differing effects of type I IFN signaling on host defense of the respiratory tract.
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影响因子：
3.7
作者：
Cigana C;Curcurù L;Leone MR;Ieranò T;Lorè NI;Bianconi I;Silipo A;Cozzolino F;Lanzetta R;Molinaro A;Bernardini ML;Bragonzi A
通讯作者：
Bragonzi A
影响因子：
56.9
作者：
Ernst, RK;Yi, EC;Miller, SI
通讯作者：
Miller, SI
DOI：
10.1513/pats.200803-025hr
发表时间：
2008-09-15
期刊：
Proceedings of the American Thoracic Society
影响因子：
--
作者：
Franks, Teri J;Colby, Thomas V;Williams, Mary C
通讯作者：
Williams, Mary C
影响因子：
64.8
作者：
Alexopoulou, L;Holt, AC;Flavell, RA
通讯作者：
Flavell, RA
影响因子：
3.1
作者：
BUKHOLM, G;BERDAL, BP;DEGRE, M
通讯作者：
DEGRE, M