Higher Risk of Anxiety and Depression in Women with Adenomyosis as Compared with Those with Uterine Leiomyoma.
Higher Risk of Anxiety and Depression in Women with Adenomyosis as Compared with Those with Uterine Leiomyoma.
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与子宫肌瘤患者相比，子宫腺肌病患者焦虑和抑郁的风险更高
DOI：
10.3390/jcm11092638
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发表时间：
2022-05-07
影响因子：
3.9
通讯作者：
中科院分区：
文献类型：
--
作者：
子宫腺肌病的主要症状可能会对身心健康和生活质量（QOL）产生不利影响。然而，关于这一主题的研究很少。本研究评估子宫腺肌病对焦虑、抑郁和生活质量的影响。患有子宫腺肌病（n = 90）或平滑肌瘤（n = 59）的参与者完成了问卷调查，包括疼痛视觉模拟量表（VAS）、医院焦虑和抑郁量表（HADS）和简明量表（SF）-36。比较两组患者HADS焦虑、抑郁阳性率、躯体和心理总分及SF-36的8个分量表评分。子宫腺肌病患者焦虑症状的发生率为28.9%（对照组为10.2%; OR = 3.589，95%CI：1.375-9.367），10%的患者表现为中重度症状。抑郁症状的发生率为14.4%（对照组为3.4%，OR = 4.812，95% CI：1.044-22.168）。病例组PCS和MCS评分均显著低于对照组。子宫腺肌病患者焦虑的危险因素为就业（OR = 6.393，95% CI：1.153-35.440）和肛周疼痛（OR = 25.419，95% CI：2.504-258.024），抑郁的危险因素为肛周疼痛（OR = 15.208，95% CI：3.050-75.836）。与子宫肌瘤相比，子宫腺肌病患者焦虑和抑郁的风险更高，生活质量更差。
The main symptoms of adenomyosis may adversely affect physical and mental health and quality of life (QOL). However, studies are few on this topic. This study evaluated the effect of adenomyosis on anxiety, depression, and QOL. Participants with adenomyosis (n = 90) or leiomyoma (n = 59) completed questionnaires, including the visual analog scale (VAS) for pain, Hospital Anxiety and Depression Scale (HADS), and Short Form (SF)-36. HADS anxiety and depression positive rates, physical (PCS) and mental (MCS) component summary scores, and eight subscale scores of SF-36 were compared between the two groups. Among patients with adenomyosis, the incidence of anxiety symptoms was 28.9% (control group, 10.2%; OR = 3.589, 95% CI: 1.375–9.367), with 10% of patients showing moderate-to-severe symptoms. The incidence of depressive symptoms was 14.4% (control group, 3.4%; OR = 4.812, 95% CI: 1.044–22.168). The case group had significantly lower PCS and MCS scores than the control group. In patients with adenomyosis, being employed (OR = 6.393, 95% CI: 1.153–35.440) and perianal pain (OR = 25.419, 95% CI: 2.504–258.024) were risk factors for anxiety, and perianal pain (OR = 15.208, 95% CI: 3.050–75.836) was a risk factor for depression. Compared with leiomyoma, adenomyosis is associated with a higher risk of anxiety and depression, with a poorer QOL.
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影响因子：
4.3
作者：
Lorençatto, C;Petta, CA;Matos, A
通讯作者：
Matos, A
影响因子：
4.7
作者：
Smarr, Karen L.;Keefer, Autumn L.
通讯作者：
Keefer, Autumn L.
影响因子：
20.8
作者：
Kessler RC;Bromet EJ
通讯作者：
Bromet EJ
影响因子：
6.7
作者：
Taran FA;Weaver AL;Coddington CC;Stewart EA
通讯作者：
Stewart EA
DOI：
10.1007/s40271-017-0284-2
发表时间：
2018-06
期刊：
The patient
影响因子：
--
作者：
Nelsen LM;Lenderking WR;Pokrzywinski R;Balantac Z;Black L;Pokras S;Enslin MB;Cooper M;Lukes AS
通讯作者：
Lukes AS