Understanding adenomyosis: a case control study.
Understanding adenomyosis: a case control study.
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DOI：
10.1016/j.fertnstert.2009.06.049
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发表时间：
2010-09
影响因子：
6.7
通讯作者：
Stewart EA
中科院分区：
文献类型：
--
作者：
Taran FA;Weaver AL;Coddington CC;Stewart EA
目的：通过与子宫肌瘤的比较，阐明子宫腺肌病的临床特点。回顾性病例对照研究。学术医学中心。这项研究包括76名患有子宫腺肌症的接受子宫切除术的妇女和152名患有子宫肌瘤但没有子宫腺肌病的妇女。医院和门诊记录的回溯性病历审查。仅有子宫腺肌病病理结果的接受子宫切除术的妇女与仅有子宫肌瘤的妇女的比较。在多变量非条件Logistic回归分析中，子宫腺肌症与较年轻的年龄(41.1岁比44.3岁)、抑郁史(57.1%比24.7%)、痛经(65.7%比42.3%)和盆腔疼痛(52.9%比21.1%)独立相关，而两组中的女性都有妇科症状。此外，在第二个多变量模型中，所有受试者的子宫重量均为150克，与子宫肌瘤患者相比，子宫腺肌病患者更有可能有抑郁(52.6%比22.2%)和子宫内膜异位症(26.3%比2.8%)的病史。与子宫肌瘤患者相比，接受子宫切除术的子宫腺肌病患者有明显的症状和病史。需要更好地了解这种疾病，以改进诊断和管理。
To elucidate the clinical profile of adenomyosis by comparison with uterine leiomyomas. Retrospective case-control study. Academic medical center. The study comprised 76 women undergoing hysterectomy with adenomyosis and 152 women with uterine leiomyomas but no adenomyosis. Retrospective medical record review of hospital and ambulatory records. Comparison of women undergoing hysterectomy with a sole pathologic finding of adenomyosis and women with leiomyomas alone. Adenomyosis was independently associated with younger age (41.1 years vs. 44.3 years), history of depression (57.1% vs. 24.7%), dysmenorrhea (65.7% vs. 42.3%), and pelvic pain (52.9% vs. 21.1%) in a multivariable unconditional logistic regression analysis compared with women with leiomyomas, where women from both groups had gynecologic symptoms. Furthermore, in a second multivariate model where all subjects had uteri weighing >150 g, women with adenomyosis were more likely to have a history of depression (52.6% vs. 22.2%) and endometriosis (26.3% vs. 2.8%) compared with women with leiomyomas. Women undergoing hysterectomy with a histologic diagnosis of adenomyosis have a distinct symptomatology and medical history compared with women with leiomyomas. Better understanding of this disease is required to improve diagnosis and management.
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影响因子：
19.7
作者：
Pelage, JP;Jacob, D;Le Dref, O
通讯作者：
Le Dref, O
影响因子：
6.1
作者：
Bergholt, T;Eriksen, L;Hertz, JB
通讯作者：
Hertz, JB
影响因子：
7.2
作者：
Levgur, M;Abadi, MA;Tucker, A
通讯作者：
Tucker, A
影响因子：
6.1
作者：
Parazzini, F;Vercellini, P;Crosignani, PG
通讯作者：
Crosignani, PG
影响因子：
1.8
作者：
Obenson, K;Abreo, F;Grafton, WD
通讯作者：
Grafton, WD