Environmental air pollution and chronic rhinosinusitis: A systematic review.
Environmental air pollution and chronic rhinosinusitis: A systematic review.
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DOI：
10.1002/lio2.774
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发表时间：
2022-04
影响因子：
1.9
通讯作者：
Ramanathan, Murugappan, Jr.
中科院分区：
文献类型：
--
作者：
Leland, Evelyn M.;Vohra, Varun;Seal, Stella M.;Zhang, Zhenyu;Ramanathan, Murugappan, Jr.
慢性鼻-鼻窦炎(CRS)是一种高发、高负担的疾病。病理生理学尚未完全阐明，但环境污染物已被认为影响疾病过程中的炎症成分。该综述旨在总结环境污染在CRS发病和疾病严重程度中的作用。按照系统审查和荟萃分析指南的首选报告项目进行了系统审查。2021年8月对PubMed、EMBASE、Cochrane图书馆、Web of Science和Scope us数据库进行了查询。报告CRS空气污染暴露的原始文章包括在内。排除其他形式的鼻窦疾病。文献检索共产生11,983篇文章，其中10篇符合纳入标准。评估的结果包括发病率/患病率、疾病严重程度、生活质量和组织病理学/微生物变化。接触空气污染物与CRS的几率较高有关，特别是与颗粒物(PM)接触有关。不断增加的空气污染暴露也与疾病严重程度恶化和可检测到的组织病理学变化有关。对生活质量的影响不那么明显。空气污染(特别是PM)与CRS的发病率/患病率和疾病严重程度相关，并与CRS组织样本的组织病理学变化有关。有必要进行进一步的研究，以更好地了解空气污染成分可能导致CRS和2型炎症的机制。3最近的证据表明，空气污染在CRS的发生和严重程度中发挥了作用，最显著的是与PM2.5暴露有关。这篇系统性的综述支持了先前的CRS体内和体外污染模型。这项研究进一步补充了现有的文献，表明暴露在空气污染中对健康有许多负面影响，包括对上呼吸道疾病、下呼吸道疾病、心脏病以及总体发病率和死亡率的影响。
Chronic rhinosinusitis (CRS) is a highly prevalent and burdensome disease. The pathophysiology is not fully elucidated, but environmental pollutants have been suggested to impact the inflammatory component of the disease process. This review aims to summarize the role of environmental pollution in CRS onset and disease severity. A systematic review was performed following Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines. PubMed, EMBASE, Cochrane Library, Web of Science, and Scopus databases were queried in August 2021. Original articles reporting on air pollution exposure in CRS were included. Other forms of sinonasal disease were excluded. Literature search produced 11,983 articles, of which 10 met inclusion criteria. Outcomes evaluated included incidence/prevalence, disease severity, quality of life, and histopathologic/microbial changes. Air pollutant exposure was associated with higher odds of CRS, particularly with particulate matter (PM) exposure. Increasing air pollution exposure was also associated with worsened disease severity and detectable histopathologic changes. Impact on quality of life was less clear. Air pollution (particularly PM) is correlated with CRS incidence/prevalence and disease severity, with evidence of histopathologic changes in CRS tissue samples. Further research is warranted to better understand the mechanisms by which air pollution components may cause CRS and type 2 inflammation. 3a Recent evidence suggests a role for air pollution in the onset and severity of CRS, most notably with relation to PM2.5 exposure. This systematic review supports previous in vitro and in vivo models of pollution in CRS. This study further adds to the existing body of literature demonstrating the many negative health impacts of exposure to air pollution, including impacts on upper airway disease, lower airway disease, cardiac disease, and overall morbidity and mortality.
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影响因子：
5.4
作者：
Kim H;Kim J;Kim S;Kang SH;Kim HJ;Kim H;Heo J;Yi SM;Kim K;Youn TJ;Chae IH
通讯作者：
Chae IH
自我报告的慢性鼻窦炎对健康相关生活质量的影响：基于人群的调查
影响因子：
3.7
作者：
Fu QL;Ma JX;Ou CQ;Guo C;Shen SQ;Xu G;Shi J
通讯作者：
Shi J
影响因子：
6.4
作者：
Mady, Leila J.;Schwarzbach, Hannah L.;Lee, Stella E.
通讯作者：
Lee, Stella E.
影响因子：
14.2
作者：
de Loos, Dirk Dietz;Lourijsen, Evelijn S.;Fokkens, Wytske J.
通讯作者：
Fokkens, Wytske J.
影响因子：
10.4
作者：
Logue JM;Price PN;Sherman MH;Singer BC
通讯作者：
Singer BC