Mapping single-cell-substrate interactions by surface plasmon resonance microscopy.

Mapping single-cell-substrate interactions by surface plasmon resonance microscopy.
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DOI:
10.1021/la301712h
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发表时间:
2012-09-18
期刊:
Langmuir : the ACS journal of surfaces and colloids
影响因子:
--
通讯作者:
Tao N
Tao N
中科院分区:
其他
文献类型:
--
作者:
Wang W;Wang S;Liu Q;Wu J;Tao N

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我们报告的成像与亚细胞空间分辨率的单个细胞的细胞基质粘附。引入渗透压以向附着于基底的细胞提供可控的机械刺激,并使用高分辨率表面等离子体共振显微镜来绘制细胞的响应,由此确定局部细胞-基底粘附。除了高空间分辨率外,该方法是非侵入性和快速的,并且允许连续映射细胞-基质相互作用和单细胞运动。
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