Towards the genetic architecture of seed lipid biosynthesis and accumulation in Arabidopsis thaliana.
Towards the genetic architecture of seed lipid biosynthesis and accumulation in Arabidopsis thaliana.
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DOI：
10.1038/hdy.2011.54
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发表时间：
2012-02
期刊：
影响因子：
3.8
通讯作者：
Bancroft, I.
中科院分区：
文献类型：
--
作者：
O'Neill, C. M.;Morgan, C.;Hattori, C.;Brennan, M.;Rosas, U.;Tschoep, H.;Deng, P. X.;Baker, D.;Wells, R.;Bancroft, I.
我们报告了6个拟南芥重组自交群体种子油质量和数量的定量遗传分析，其中亲本加入来自不同的地理来源，并根据种子油含量和脂质组成的变化进行选择。虽然大多数涉及脂质生物合成的生化步骤是已知的，并且已经确定了关键基因，但导致最终油成分和总量的过程的调节尚不清楚。通过使用物理锚定标记，可以比较不同人群的结果。共检测到219个数量性状位点（QTL），其中81个达到显著水平（P<0.001）。其中一些与先前鉴定的QTL共定位，但也鉴定了许多新的QTL。这些结果突出了在多个群体中研究性状的重要性，这将有助于更好地了解自然变异对表型遗传结构的贡献。
We report the quantitative genetic analysis of seed oil quality and quantity in six Arabidopsis thaliana recombinant inbred populations, in which the parent accessions were from diverse geographical origins, and were selected on the basis of variation for seed oil content and lipid composition. Although most of the biochemical steps involved in lipid biosynthesis are known and the key genes have been identified, the regulation of the processes that results in the final oil composition and total amount is not understood. By using physically anchored markers it was possible to compare results across populations. A total of 219 quantitative trait loci (QTLs) were identified, of which 81 were significant at P<0.001. Some of these colocalise with QTLs identified previously, but many novel QTLs were also identified. The results highlight the importance of studying traits in multiple populations, which will lead to a better understanding of the contribution that natural variation makes to the genetic architecture of a phenotype.
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