Physical activity and cancer.

Physical activity and cancer.
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DOI:
10.1007/s11912-012-0265-5
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发表时间:
2012-12
影响因子:
4.7
通讯作者:
Bernstein, Leslie
Bernstein, Leslie
中科院分区:
医学2区
文献类型:
--
作者:
Clague, Jessica;Bernstein, Leslie

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流行病学证据继续积累,表明身体活动与癌症风险、进展和死亡率有关。最近的研究表明,久坐行为可能独立影响癌症风险;他们还关注可能解释与体力活动相关的因素,包括癌症风险因素以及是否存在与癌前病变的相关性。尽管在研究体力活动与癌症之间的关联方面付出了巨大的努力,但由于对各项研究中体力活动的评估不一致,以及对不同人群亚组(例如,由身体大小,年龄或性别定义)或肿瘤亚组(器官位置,受体状态或分子亚型)的影响差异的考虑不完整,以及是否有其他因素解释了研究结果,文献受到了阻碍。显然,需要适当改变活动水平的公共卫生建议;不幸的是,在这个时候,我们没有确切的体力活动处方给公众。
Epidemiological evidence continues to accumulate on the benefits of physical activity in relation to cancer risk, progression and mortality. Recent studies suggest that sedentary behavior may independently affect cancer risk; they also focus on factors that may explain associations with physical activity, including cancer risk factors and whether associations exist for precancerous lesions. Despite enormous efforts to examine associations between physical activity and cancer, the literature is hindered by inconsistent assessment of physical activity across studies, and incomplete consideration of variation of effects across population subgroups (for example, defined by body size, age or sex) or tumors subgroups (organ location, receptor status, or molecular subtype), and whether other factors explain study results. Clearly, public health recommendations for appropriate changes in activity levels are needed; unfortunately, at this time, we have no exact physical activity prescription to give to the public.
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