Cardiovascular PET/MRI: Technical Considerations and Outlook

Cardiovascular PET/MRI: Technical Considerations and Outlook
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心血管 PET/MRI:技术考虑因素和展望

DOI:
10.1007/s12410-017-9435-z
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发表时间:
2017
影响因子:
0.9
通讯作者:
C. Rischpler
C. Rischpler
中科院分区:
--
文献类型:
--
作者:
S. G. Nekolla;S. van Marwick;S. Schachoff;K. P. Kunze;C. Rischpler

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回顾的目的我们的目标是提供洞察心脏PET/MRI的当前和未来的应用和后勤问题时,应该考虑使用这种仍然是新的technology.Recent FindingsSince他们的介绍约15年前,PET/CT和SPECT/CT混合成像设备看到了很高的临床利用率,这是由肿瘤学驱动的。幸运的是,在临床环境中的基本可用性使心脏成像的角度调查,并促进了许多研究活动。鉴于心脏MRI是一个非常有吸引力的研究领域,临床应用越来越多,PET/MRI提高了对具有协同应用的创新成像场景的期望。将分子成像与多种PET试剂和MRI的高时间和空间分辨率相结合非常适合于新的应用,特别是电离辐射的负担减轻,并且可能缺乏造影剂。SummaryThe技术的复杂性和相应的大量金钱投资导致直到今天的可用性和经验有限。然而,这些系统的潜力目前是无与伦比的,因为它们真正实现了“两全其美”的方法。
Purpose of ReviewWe aim to provide insights into current and future applications of cardiac PET/MRI and the logistical issues one should consider when implementing a program using this still novel technology.Recent FindingsSince their introduction around 15 years ago, PET/CT and SPECT/CT hybrid imaging devices saw high clinical utilization, which was driven clearly by oncology. Fortunately, the basic availability in a clinical setting enabled the investigation of the cardiac imaging perspective and facilitated numerous research activities. Given the fact that cardiac MRI is a very attractive research field with an increasing clinical utilization, PET/MRI raised the expectation of innovative imaging scenarios with synergistic applications. Integrating molecular imaging with a multitude of PET agents and the high temporal and spatial resolution of MRI are ideally suited for novel applications having especially a reduced burden of ionizing radiation and potentially a lack of contrast media in mind.SummaryThe technical complexity and consequentially the considerable amount of monetary investment resulted until today in a limited availability and experience. However, the potential of these systems are currently unsurpassed as they really implement a “best of both worlds” approach.
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