The effect of black tea on blood pressure: a systematic review with meta-analysis of randomized controlled trials.
The effect of black tea on blood pressure: a systematic review with meta-analysis of randomized controlled trials.
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DOI：
10.1371/journal.pone.0103247
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发表时间：
2014
期刊：
影响因子：
3.7
通讯作者：
Draijer R
中科院分区：
文献类型：
--
作者：
Greyling A;Ras RT;Zock PL;Lorenz M;Hopman MT;Thijssen DH;Draijer R
流行病学证据表明，饮用茶树红茶可以降低患心血管疾病的风险。然而，关于饮茶对血压（BP）影响的干预研究报告的结果不一致。我们的目标是对饮茶对血压影响的受控人类干预研究进行系统文献综述和荟萃分析。我们系统地检索了 Medline、Biosis、Chemical Abstracts 和 EMBASE 数据库，直至 2013 年 7 月。为了纳入研究，研究必须满足以下预先定义的标准：1) 成人安慰剂对照设计，2) 至少 1 周饮用红茶作为唯一干预措施，3) 报告对收缩压 (SBP) 或舒张压 (DBP) 或两者的影响。使用随机效应模型来计算红茶对血压的总体影响。 11 项研究（12 个干预组、378 名受试者、4-5 杯茶的剂量）符合我们的纳入标准。经常喝茶对收缩压的汇总平均影响为-1.8毫米汞柱（95% CI：-2.8，-0.7；P = 0.0013），对舒张压的汇总平均影响为-1.3毫米汞柱（95% CI：-1.8，-0.8；P<0.0001）。在协变量分析中，我们发现茶叶制备方法（茶提取物粉末与叶茶）、基线收缩压和舒张压以及研究的质量评分影响茶干预的效果大小（所有 P<0.05）。没有发现发表偏倚的证据。我们的荟萃分析表明，经常饮用红茶可以降低血压。尽管影响很小，但这种影响可能对人群心血管健康很重要。
Epidemiological evidence has linked consumption of black tea, produced from Camellia sinensis, with a reduced risk of cardiovascular diseases. However, intervention studies on the effects of tea consumption on blood pressure (BP) have reported inconsistent results. Our objective was to conduct a systematic literature review with meta-analysis of controlled human intervention studies examining the effect of tea consumption on BP. We systematically searched Medline, Biosis, Chemical Abstracts and EMBASE databases through July 2013. For inclusion, studies had to meet the following pre-defined criteria: 1) placebo controlled design in human adults, 2) minimum of 1 week black tea consumption as the sole intervention, 3) reported effects on systolic BP (SBP) or diastolic BP (DBP) or both. A random effects model was used to calculate the pooled overall effect of black tea on BP. Eleven studies (12 intervention arms, 378 subjects, dose of 4–5 cups of tea) met our inclusion criteria. The pooled mean effect of regular tea ingestion was −1.8 mmHg (95% CI: −2.8, −0.7; P = 0.0013) for SBP and −1.3 mmHg (95% CI: −1.8, −0.8; P<0.0001) for DBP. In covariate analyses, we found that the method of tea preparation (tea extract powders versus leaf tea), baseline SBP and DBP, and the quality score of the study affected the effect size of the tea intervention (all P<0.05). No evidence of publication bias could be detected. Our meta-analysis indicates that regular consumption of black tea can reduce BP. Although the effect is small, such effects could be important for cardiovascular health at population level.
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影响因子：
4.9
作者：
Hodgson, JM;Puddey, IB;Jordan, N
通讯作者：
Jordan, N
影响因子：
4.9
作者：
Grassi, Davide;Mulder, Theo P. J.;Ferri, Claudio
通讯作者：
Ferri, Claudio
DOI：
10.1016/0197-2456(86)90046-2
发表时间：
1986-09-01
期刊：
CONTROLLED CLINICAL TRIALS
影响因子：
--
作者：
DERSIMONIAN, R;LAIRD, N
通讯作者：
LAIRD, N
影响因子：
3.6
作者：
Dong, Jia-Yi;Tong, Xing;Qin, Li-Qiang
通讯作者：
Qin, Li-Qiang
影响因子：
4.2
作者：
Hodgson, JM;Devine, A;Prince, RL
通讯作者：
Prince, RL