Microalgae as sources of carotenoids.

Microalgae as sources of carotenoids.
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DOI:
10.3390/md9040625
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发表时间:
2011
期刊:
影响因子:
5.4
通讯作者:
Malcata FX
Malcata FX
中科院分区:
医学2区
文献类型:
--
作者:
Guedes AC;Amaro HM;Malcata FX

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海洋微藻是制药、食品和化妆品等多种药物的天然来源,其中包括类胡萝卜素等。越来越多的实验证据证实,这些化合物可以在预防(甚至治疗)人类疾病和健康状况方面发挥重要作用,例如癌症、心血管问题、动脉粥样硬化、类风湿性关节炎、肌肉营养不良、白内障和一些神经疾病。可能解释这种良好生物活性的潜在特征是其内在的抗氧化、抗炎和抗肿瘤特性。在这篇受邀的综述中,从生理和加工两个角度描述和讨论了有关微藻合成类胡萝卜素的最重要的问题。目前的知识差距以及在不久的将来与这一日益增长的感兴趣的领域有关的技术机会也是以批判性的方式提出的。
Marine microalgae constitute a natural source of a variety of drugs for pharmaceutical, food and cosmetic applications—which encompass carotenoids, among others. A growing body of experimental evidence has confirmed that these compounds can play important roles in prevention (and even treatment) of human diseases and health conditions, e.g., cancer, cardiovascular problems, atherosclerosis, rheumatoid arthritis, muscular dystrophy, cataracts and some neurological disorders. The underlying features that may account for such favorable biological activities are their intrinsic antioxidant, anti-inflammatory and antitumoral features. In this invited review, the most important issues regarding synthesis of carotenoids by microalgae are described and discussed—from both physiological and processing points of view. Current gaps of knowledge, as well as technological opportunities in the near future relating to this growing field of interest, are also put forward in a critical manner.
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