Remediation of depression-related cognitive impairment: cognitive control training as treatment augmentation

Remediation of depression-related cognitive impairment: cognitive control training as treatment augmentation
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抑郁相关认知障碍的补救:认知控制训练作为治疗增强

DOI:
10.1080/14737175.2018.1537783
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发表时间:
2018
影响因子:
4.3
通讯作者:
E. Koster
E. Koster
中科院分区:
医学3区
文献类型:
--
作者:
N. Van den Bergh;K. Hoorelbeke;R. de Raedt;E. Koster

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摘要引言:尽管有几种针对抑郁症复发的循证干预措施,但复发率仍然很高,预防复发的计划仍然很少。为了提高效力,针对潜在脆弱性因素的新技术可能是一个有希望的途径。抑郁症与执行功能障碍有关,而执行功能障碍又与不良的心理社会结果和更多的重复性消极思维(RNT)有关,这是复发的关键脆弱因素。本文探讨赤字的认知控制作为一个潜在的可修改的因果机制抑郁症。涵盖的领域:认知控制和RNT之间的相互作用的研究概述,评估抑郁症患者的训练认知控制的潜力。认知控制训练(CCT)或其他旨在补救执行功能的技术,提供了一种有趣的方法来检查抑郁相关症状中执行功能的因果关系,如情绪调节和心理社会功能。评估CCT的临床效用。专家评论:CCT的临床效用有新的证据,但需要更多的大规模纵向研究。本节讨论了如何适应性起搏听觉序列加法测试(PASAT)可以作为一种技术,可以与心理和生物干预相结合,以提高抑郁症治疗的整体效果。
ABSTRACT Introduction: Despite several available evidence-based interventions for major depression relapse, rates remain high and relapse prevention programs are still scarce. To increase effectiveness, novel techniques that target underlying vulnerability factors may be a promising avenue. Depression is associated with impairments in executive functioning, which is in turn associated with poor psychosocial outcomes and more Repetitive Negative Thinking (RNT), a key vulnerability factor for relapse. This paper examines deficits in cognitive control as a potentially modifiable causal mechanism for depression. Areas covered: An overview of studies on the interplay between cognitive control and RNT is presented, assessing the potential of training cognitive control in depressed individuals. Cognitive Control Training (CCT), or other techniques aimed at remediating executive functioning, provides an interesting way to examine the causal status of executive functions in depression-related symptoms, such as emotion regulation and psychosocial functioning. The clinical utility of CCT is assessed. Expert commentary: There is emerging evidence for clinical utility of CCT but more large-scale, longitudinal studies are required. The section discusses how the adaptive Paced Auditory Serial Addition Test (PASAT) can be used as a technique that can be combined with psychological as well as biological interventions, to increase overall effectiveness of treatment for depression.
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