Does adverse family environment or sex matter in the salivary cortisol responses to anticipatory stress?

Does adverse family environment or sex matter in the salivary cortisol responses to anticipatory stress?
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不良的家庭环境或性别对唾液皮质醇对预期压力的反应是否重要?

DOI:
10.1016/s0165-1781(02)00182-8
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发表时间:
2002
影响因子:
11.3
通讯作者:
Kirillovac,GalinaP
Kirillovac,GalinaP
中科院分区:
医学2区
文献类型:
--
作者:
Hardie,ThomasL;Moss,HowardB;Vanyukov,MichaelM;Yao,JeffreyK;Kirillovac,GalinaP

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我们以前报道过,在预期适度的压力源时,药物依赖父亲(HR)的青春期前儿子相对于对照组男孩表现出减少的唾液皮质醇反应。没有关于HR父亲的青春期前女儿的预期唾液皮质醇反应的数据。此外,我们假设HR青年压力反应的减少可能是对压力家庭环境的适应。因此,在本报告中,我们研究了家庭环境在HR男孩和女孩预期唾液皮质醇反应中的作用,以及它们与家庭环境中痛苦程度的关系。与性别无关,HR儿童预期皮质醇反应减弱。女孩在压力前和压力后唾液皮质醇浓度显著升高。然而,与我们的预期相反,我们无法证明唾液皮质醇反应与家庭环境的测量之间存在关联。这些结果表明,青春期前儿童唾液皮质醇动态可能存在性别差异;然而,当前家庭环境的功能状态似乎与皮质醇反应性无关。
We previously reported that in anticipation of a modest stressor, preadolescent sons of drug-dependent fathers (HR) demonstrated a diminished salivary cortisol response relative to comparison boys. No data were available concerning anticipatory salivary cortisol responses in preadolescent daughters of HR fathers. Additionally, we hypothesized that diminished stress responses in HR youth might be an adaptation to a stressful family environment. Consequently, in this report we have examined the role of family environment in the anticipatory salivary cortisol responses in both HR boys and girls as well as their association with a measure of distress in the family environment. Independent of sex, HR children had diminished anticipatory cortisol responses. Girls had significantly higher salivary cortisol concentrations, pre- and post-stressor. However, contrary to our expectation, we could not demonstrate an association between salivary cortisol responses and the measures of the family environment. These results suggest that there may be a sex difference in salivary cortisol dynamics in preadolescent children; however, the functional status of the current family environment does not appear to be related to cortisol reactivity.
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DOI: --
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