Mitochondrial DNA control region sequencing of the critically endangered Hainan gibbon (Nomascus hainanus) reveals two female origins and extremely low genetic diversity.

Mitochondrial DNA control region sequencing of the critically endangered Hainan gibbon (Nomascus hainanus) reveals two female origins and extremely low genetic diversity.
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极度濒危海南长臂猿(Nomascus hainanus)的线粒体 DNA 控制区测序揭示了两种雌性起源和极低的遗传多样性

DOI:
10.1080/23802359.2021.1909432
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发表时间:
2021-04-07
期刊:
Mitochondrial DNA. Part B, Resources
影响因子:
--
通讯作者:
Zhou J
Zhou J
中科院分区:
其他
文献类型:
--
作者:
Guo Y;Peng D;Han L;Liu T;Li G;Garber PA;Zhou J

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海南长臂猿(Nomariahainanus)是中国特有的,也是世界上最稀有的猿类。野生种群总数仅为33只。在本研究中,我们对12只野生海南长臂猿的线粒体DNA控制区进行了测序,这些长臂猿代表了其余五个群体中的三个社会群体。通过群体遗传学分析,发现T、C、A和G四种核苷酸所占比例分别为29.0%、27.2%、31.9%和11.9%。线粒体DNA D环区的高变片段(长度为1005 bp),表明5个可变位点(点突变),在12个样本中仅存在两种单倍型。我们观察到海南长臂猿的遗传多样性低于任何其他野生灵长类种群,检测到的两个单倍型,代表两个祖先谱系。这些发现对于提出有效的保护策略来保护这种极度濒危的猿类物种具有重要意义。
The Hainan gibbon (Nomascus hainanus) is endemic to China and is the world’s rarest ape. The remaining wild population totals only 33 individuals. In the current study, we sequenced the Mitochondrial DNA control region of 12 wild Hainan gibbons representing three social groups of the five remaining groups. By conducting population genetic analyses, we found that the proportion of four nucleotides (T, C, A and G) were 29.0%, 27.2%, 31.9% and 11.9%, respectively. Hypervariable segments of the mtDNA D-loop region (1005 bp in length), indicated five variable sites (a point mutation), with only two haplotypes present among the 12 samples. We observed that the genetic diversity of Hainan gibbons is lower than that reported in any other wild primate population, and that the two haplotypes detected, represent two ancestral lineages. These findings have important implications for proposing effective conservation strategies to protect this Critically Endangered ape species.
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