Effects of endurance training on total fat oxidation in elderly persons.
Effects of endurance training on total fat oxidation in elderly persons.
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耐力训练对老年人总脂肪氧化的影响。
DOI：
10.1152/jappl.1994.76.6.2281
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发表时间：
1994
期刊：
影响因子：
--
通讯作者：
Calles-Escandon,J
中科院分区：
文献类型：
--
作者：
Poehlman,ET;Gardner,AW;Arciero,PJ;Goran,MI;Calles-Escandon,J
我们研究了8周耐力训练对基础脂肪氧化水平的影响及其与去甲肾上腺素（NE）动力学、静息代谢率（RMR）和18名健康老年人（66.1 ± 1.4岁; 10名男性，8名女性）身体成分变化的关系。脂肪酸出现率和全身脂肪氧化测定[14 C]棕榈酸输注和间接量热法，NE动力学测定[3 H]NE的输注，RMR测定通风罩技术，和身体组成测定水下称重。耐力训练使峰值耗氧量增加了11%（1.9 +/- 0.1至2.1 +/- 0.1 l/min; P < 0.01），RMR增加了7%（1.20 +/- 0.02至1.28 +/- 0.02 kcal/min; P < 0.01）。耐力训练使NE出现率增加35%（0.51 +/- 0.04至0.69 +/- 0.04微克/分钟; P < 0.01），而NE清除率没有变化。耐力训练使脂肪氧化增加了22%（201.0 +/- 11.2 vs. 244.0 +/- 15.2 mumol/min; P < 0.01），但没有改变脂肪酸的出现率。约三分之二的脂肪氧化增加的变化（r2 = 0.65）可由NE出现率增加（r2 = 0.51; P < 0.01）和去脂体重变化（r2 = 0.14; P < 0.01）解释。我们得出结论：1）耐力训练使老年人体内基础底物利用率向更高的脂肪氧化转变，2）增强的脂肪氧化与交感神经系统活性增加和无脂肪质量改变有关。
We examined the influence of 8 wk of endurance training on basal levels of fat oxidation and its association with changes in norepinephrine (NE) kinetics, resting metabolic rate (RMR), and body composition in 18 healthy elderly persons (66.1 +/- 1.4 yr; 10 men, 8 women). Fatty acid appearance rate and total body fat oxidation were determined from [14C]palmitate infusion and indirect calorimetry, NE kinetics were determined from infusions of [3H]NE, RMR was determined from the ventilated hood technique, and body composition was determined from underwater weighing. Endurance training increased peak oxygen consumption by 11% (1.9 +/- 0.1 to 2.1 +/- 0.1 l/min; P < 0.01) and increased RMR by 7% (1.20 +/- 0.02 to 1.28 +/- 0.02 kcal/min; P < 0.01). Endurance training increased NE appearance rate by 35% (0.51 +/- 0.04 to 0.69 +/- 0.04 micrograms/min; P < 0.01), whereas no change in NE clearance was noted. Endurance training increased fat oxidation by 22% (201.0 +/- 11.2 vs. 244.0 +/- 15.2 mumol/min; P < 0.01) but did not alter fatty acid appearance rate. Approximately two-thirds of the variation (r2 = 0.65) for the increase in fat oxidation was explained by increased NE appearance rate (r2 = 0.51; P < 0.01) and changes in fat-free weight (r2 = 0.14; P < 0.01). We conclude that 1) endurance training shifts in vivo basal substrate utilization toward greater fat oxidation in elderly individuals and 2) enhanced fat oxidation is associated with increased activity of the sympathetic nervous system and alterations in fat-free mass.
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影响因子：
15.9
作者：
P. Molé;L. B. Oscai;J. Holloszy
通讯作者：
J. Holloszy
影响因子：
9.8
作者：
DESPRES, JP;BOUCHARD, C;THERIAULT, G
通讯作者：
THERIAULT, G
年龄和体力活动水平对血浆去甲肾上腺素动力学的影响。
DOI：
10.1152/ajpendo.1990.258.2.e256
发表时间：
1990
期刊：
The American journal of physiology
影响因子：
--
作者：
Poehlman,ET;McAuliffe,T;DanforthJr,E
通讯作者：
DanforthJr,E
激素和代谢对运动的适应
DOI：
--
发表时间：
1983
期刊：
影响因子：
--
作者：
H. Galbo
通讯作者：
H. Galbo
影响因子：
15.9
作者：
GROOP, LC;BONADONNA, RC;DEFRONZO, RA
通讯作者：
DEFRONZO, RA