Interaction of propidium iodide with graphene oxide and its application for live cell staining

Interaction of propidium iodide with graphene oxide and its application for live cell staining
复制标题

碘化丙啶与氧化石墨烯的相互作用及其在活细胞染色中的应用

DOI:
10.1016/j.carbon.2014.01.029
复制
发表时间:
2014-05
期刊:
影响因子:
10.9
通讯作者:
Sun, Shiguo
Sun, Shiguo
中科院分区:
材料科学2区
文献类型:
--
作者:
Liu, Fengyu;Gao, Yulong;Li, Haiju;Sun, Shiguo

文献摘要

参考文献

被引文献

相似文献

在水溶液中加入氧化石墨烯(GO)可以有效地猝灭碘化丙啶(PI)的荧光,这是由于形成了一种名为GO-PI的物理吸附材料。在上述溶液中加入一定量的DNA/RNA后,可以观察到约80倍的荧光增强。同时,发现GO-PI可以进入细胞核并染色活的人乳腺癌细胞MCF-7的DNA/RNA,而PI单独在对照实验中不能穿过细胞膜,证明GO可以用作用于活细胞染色的有效PI递送纳米材料。
The fluorescence of propidium iodide (PI) can be effectively quenched with the addition of graphene oxide (GO) in aqueous solution, due to the formation of a physical adsorption material named GO–PI. A fluorescence enhancement of approximately 80 times can be observed after addition of a certain amount of DNA/RNA into the above-mentioned solution. Meanwhile, it is found that the GO–PI can enter into the nuclei and stain the DNA/RNA of living human breast cancer cells MCF-7, while PI alone cannot cross the cellular membrane in the control experiment, demonstrating GO can be employed to be an efficient PI delivery nanomaterial for live cell staining.
使用石墨烯保护 DNA 在细胞传递过程中不被裂解
DOI: 10.1039/b926893f
发表时间: 2010-01-01
影响因子: 4.9
作者:
Lu, Chun-Hua;Zhu, Chun-Ling;Yang, Huang-Hao
通讯作者: Yang, Huang-Hao
DOI: 10.4049/jimmunol.136.2.412
发表时间: 1986-01
影响因子: 4.4
作者:
J. B. Turpen;P. Smith
通讯作者: J. B. Turpen;P. Smith
DOI: 10.1021/ma300732m
发表时间: 2012-05
期刊: Macromolecules
影响因子: 5.5
作者:
Tadanori Kurosawa;Yi-Cang Lai;Tomoya Higashihara;M. Ueda;Cheng‐Liang Liu;Wen‐Chang Chen
通讯作者: Tadanori Kurosawa;Yi-Cang Lai;Tomoya Higashihara;M. Ueda;Cheng‐Liang Liu;Wen‐Chang Chen
DOI: 10.1002/smll.200901680
发表时间: 2010-02-22
期刊: SMALL
影响因子: 13.3
作者:
Zhang, Liming;Xia, Jingguang;Zhang, Zhijun
通讯作者: Zhang, Zhijun
DOI: 10.1007/s12274-008-8021-8
发表时间: 2008-09-01
期刊: NANO RESEARCH
影响因子: 9.9
作者:
Sun, Xiaoming;Liu, Zhuang;Dai, Hongjie
通讯作者: Dai, Hongjie