Platelets and viruses.
Platelets and viruses.
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DOI:
10.1080/09537104.2021.1887842
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发表时间:
2021-04-03
期刊:
影响因子:
3.3
通讯作者:
Mackman N
中科院分区:
文献类型:
--
作者:
Antoniak S;Mackman N
Platelets play an essential role in maintaining vascular integrity after injury. In addition, platelets contribute to the immune response to pathogens. For instance, they express receptors that mediate binding of viruses, and toll-like receptors that activate the cell in response to pathogen-associated molecular patterns. Platelets can be beneficial and/or detrimental during viral infections. They reduce blood-borne viruses by engulfing the free virus and presenting the virus to neutrophils. However, platelets can also enhance inflammation and tissue injury during viral infections. Here, we will discuss the roles of platelets in viral infection.
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