In silico prediction of neuropeptides in Hymenoptera parasitoid wasps.
In silico prediction of neuropeptides in Hymenoptera parasitoid wasps.
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膜翅目寄生蜂神经肽的计算机预测
DOI：
10.1371/journal.pone.0193561
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发表时间：
2018
期刊：
影响因子：
3.7
通讯作者：
Tian X
中科院分区：
文献类型：
--
作者：
Chang J;Zhao J;Tian X
寄生蜂是自然生态系统中种类最多的动物类群，是节肢动物的重要天敌，可用于生物防治。迄今为止，只有一个神经肽组的寄生蜂，丽翅蜂，已被确定。本研究的目的是通过使用一个成熟的工作流程，以前采用的昆虫神经肽序列预测寄生蜂更多的神经肽。基于公开数据库，从24种寄生蜂中共鉴定出517种神经肽前体，其中包括5种首次在寄生蜂中鉴定的神经肽（CNMamide、FMRFamide-like、ITG-like、iontransportpeptide-like和orcokinin B）。接下来，这些神经肽从寄生蜂进行了比较，从其他昆虫物种。系统发育分析表明，该基因在Hytera中存在一定的分化。此外，CAPA/PK家族基因的编码模式被发现与其他昆虫物种的Hytera物种之间的不同。一些神经肽在一些寄生蜂超科中没有发现（例如，sulfakinin），或者在不同的寄生物超科之间有相当大的差异（例如，sNPF）可能与寄生蜂生活中不同的生理过程有关。寄生蜂神经肽序列的研究有助于更好地理解Hypltera的系统发育关系，并进一步阐明寄生蜂神经肽信号系统的生理功能。
Parasitoid wasps of the order Hymenoptera, the most diverse groups of animals, are important natural enemies of arthropod hosts in natural ecosystems and can be used in biological control. To date, only one neuropeptidome of a parasitoid wasp, Nasonia vitripennis, has been identified. This study aimed to identify more neuropeptides of parasitoid wasps, by using a well-established workflow that was previously adopted for predicting insect neuropeptide sequences. Based on publicly accessible databases, totally 517 neuropeptide precursors from 24 parasitoid wasp species were identified; these included five neuropeptides (CNMamide, FMRFamide-like, ITG-like, ion transport peptide-like and orcokinin B) that were identified for the first time in parasitoid wasps, to our knowledge. Next, these neuropeptides from parasitoid wasps were compared with those from other insect species. Phylogenetic analysis suggested the divergence of AST-CCC within Hymenoptera. Further, the encoding patterns of CAPA/PK family genes were found to be different between Hymenoptera species and other insect species. Some neuropeptides that were not found in some parasitoid superfamilies (e.g., sulfakinin), or considerably divergent between different parasitoid superfamilies (e.g., sNPF) might be related to distinct physiological processes in the parasitoid life. Information of neuropeptide sequences in parasitoid wasps can be useful for better understanding the phylogenetic relationships of Hymenoptera and further elucidating the physiological functions of neuropeptide signaling systems in parasitoid wasps.
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影响因子：
5.2
作者：
Caers J;Verlinden H;Zels S;Vandersmissen HP;Vuerinckx K;Schoofs L
通讯作者：
Schoofs L
影响因子：
2.7
作者：
Christie, Andrew E.;Hull, J. Joe;Tassone, Erica E.
通讯作者：
Tassone, Erica E.
DOI：
10.1016/0020-1790(89)90073-5
发表时间：
1989-01-01
期刊：
INSECT BIOCHEMISTRY
影响因子：
--
作者：
MATSUMOTO, S;BROWN, MR;LEA, AO
通讯作者：
LEA, AO
影响因子：
2.6
作者：
Ons, S.;Sterkel, M.;Rivera-Pomar, R.
通讯作者：
Rivera-Pomar, R.
影响因子：
3.6
作者：
Roller, Ladislav;Cizmar, Daniel;Zitnan, Dusan
通讯作者：
Zitnan, Dusan