Alcohol dependence and anxiety disorders: what is the relationship?
Alcohol dependence and anxiety disorders: what is the relationship?
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酒精依赖和焦虑症：有什么关系？
DOI：
10.1176/ajp.151.12.1723
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发表时间：
1994
期刊：
影响因子：
--
通讯作者：
Hesselbrock,V
中科院分区：
文献类型：
--
作者：
Schuckit,MA;Hesselbrock,V
目的在这篇批判性评论中，作者评估了有关终身 DSM-III-R 焦虑症与酒精依赖之间关系的文献。许多酒精依赖者在急性或长期戒酒综合症的背景下表现出严重的焦虑症状，但尚不清楚这些焦虑状况是独立的精神疾病还是可能自行消失的暂时综合症。方法回顾了自 1975 年以来描述酗酒和焦虑症之间关系的报告，以确定 1) 终生焦虑症在酒精依赖者中是否异常普遍，2) 酗酒者的孩子比对照人群更容易患焦虑症，3) 焦虑戒酒后，这些症状可能会消失；4）终生焦虑症患者的酒精依赖率高于正常水平；5）酒精依赖和焦虑症之间存在家族交叉；6）在前瞻性研究的一般人群中，酗酒之前通常会出现焦虑症。结果：饮酒和焦虑症之间的相互作用很复杂。现有数据虽然不完善，但并不能证明终身焦虑症与酒精依赖之间存在密切关系。此外，对酗酒者的孩子和一般人群中的个体进行的前瞻性研究并未表明酒精依赖之前焦虑症的发生率很高。 结论 一些研究中的高合并症发生率可能反映了酗酒者中真正的焦虑症的混合情况，其发生率等于或略高于一般人群，以及暂时但有时严重的物质引起的焦虑综合症。
ObjectiveIn this critical review the authors evaluate the literature regarding the relationship between lifelong DSM-III-R anxiety disorders and alcohol dependence. Many alcohol-dependent individuals demonstrate severe anxiety symptoms in the context of acute or protracted abstinence syndromes, but it is unclear whether these anxiety conditions are independent psychiatric disorders or temporary syndromes likely to disappear on their own.MethodReports since 1975 describing the relationship between alcoholism and anxiety disorders were reviewed to determine whether 1) lifelong anxiety disorders are unusually prevalent among alcohol-dependent individuals, 2) children of alcoholics are more likely to develop anxiety disorders than comparison populations, 3) anxiety syndromes are likely to disappear with abstinence, 4) the rate of alcohol dependence among subjects with lifelong anxiety disorders is higher than normal, 5) there is familial crossover between alcohol dependence and anxiety disorders, and 6) alcoholism is often preceded by anxiety disorders in groups from the general population studied prospectively.ResultsThe interaction between alcohol use and anxiety disorders is complex. The available data, while imperfect, do not prove a close relationship between lifelong anxiety disorders and alcohol dependence. Further, prospective studies of children of alcoholics and individuals from the general population do not indicate a high rate of anxiety disorders preceding alcohol dependence.ConclusionsThe high rates of comorbidity in some studies likely reflect a mixture of true anxiety disorders among alcoholics at a rate equal to or slightly higher than that for the general population, along with temporary, but at times severe, substance-induced anxiety syndromes.
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DOI：
--
发表时间：
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期刊：
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影响因子：
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DOI：
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发表时间：
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期刊：
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影响因子：
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作者：
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DOI：
10.1111/j.1360-0443.1994.tb00924.x
发表时间：
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期刊：
Addiction (Abingdon, England)
影响因子：
--
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