Restriction endonuclease patterns of herpes simplex virus DNA: application to diagnosis and molecular epidemiology.

Restriction endonuclease patterns of herpes simplex virus DNA: application to diagnosis and molecular epidemiology.
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单纯疱疹病毒 DNA 的限制性核酸内切酶模式:在诊断和分子流行病学中的应用。

DOI:
10.1007/978-3-642-68949-9_17
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发表时间:
1983
影响因子:
--
通讯作者:
Tognon,M
Tognon,M
中科院分区:
医学3区
文献类型:
--
作者:
Roizman,B;Tognon,M

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从历史上看,单纯疱疹病毒(HSV)毒株可能差异很大的迹象出现在许多年前(AsheandScherp 1965; HamparandBurroughs 1969)。对于我们之一(BR),关于HSV变异性的研究开始于突变体[HSV-1(MP)]的偶然分离,该突变体将细胞从野生型病毒[HSV-1(mP)]融合到多核细胞中,导致细胞变圆和结块(HogganandRoizman 1959)。随后的研究表明,亲本和突变体在CsCl梯度中的浮力密度不同(RoizmanandRoane 1961),亲和层析(RoizmanandRoane 1963),用特异性抗血清中和(RoizmanandRoane 1963),积累糖蛋白VP 8(gC)的能力(海涅等,1974),并最终涉及除了糖蛋白VP 8(gC)积累之外还与细胞融合有关的几个遗传基因座(Ruyechanet al.1979)。HSV代表两种病毒HSV-1和HSV-2的发现(Schneweiss 1962;Dowdleet al. 1967),以及对每种病毒的分离株和突变体的研究(Ejercito et al. 1968;Heineet al. 1974;Sethetal. 1974; TerniandRoizman 1970),加强了HSV毒株在许多特征上不同的假设。
Historically, the indications that herpes simplex virus (HSV) strains may vary considerably emerged many years ago (AsheandScherp1965;HamparandBurroughs1969). For one of us (BR), the studies on the variability of HSV began with a chance isolation of a mutant [HSV-1 (MP)] that fused cells into polykaryocytes from a wild type virus [HSV-l (mP)] which caused cells to round and clump (HogganandRoizman1959). Subsequent studies showed that the parent and mutant differed with respect to buoyant density in CsCl gradients (RoizmanandRoane1961), affinity chromatography (RoizmanandRoane1963), neutralization with specific antisera (RoizmanandRoane1963), the ability to accumulate glycoprotein VP8(gC) (Heine et al. 1974) and, ultimately, with respect to several genetic loci concerned with cell fusion in addition to accumulation of glycoprotein VP8(gC) (Ruyechanet al. 1979). The discovery that HSV represents two viruses, HSV-1 and HSV-2 (Schneweiss1962;Dowdleet al. 1967), and studies on isolates and mutants of each (Ejercitoet al. 1968;Heineet al. 1974;Sethetal. 1974;TerniandRoizman1970), reinforced the hypothesis that HSV strains vary in a number of characteristics.
单纯疱疹病毒染色体的反向重复。
DOI: 10.1101/sqb.1974.039.01.080
发表时间: 1975
期刊: Cold Spring Harbor symposia on quantitative biology
影响因子: --
作者:
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托儿所内 1 型单纯疱疹病毒的传播,通过 DNA 对新生儿进行病毒分离鉴定
DOI: --
发表时间: 1978
期刊: The Lancet
影响因子: --
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单纯疱疹脑炎颞丛:通过限制性核酸内切酶切割病毒 DNA 进行研究。
DOI: --
发表时间: 1980
影响因子: 6.4
作者:
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通讯作者: M. Hirsch
DOI: --
发表时间: 1978
影响因子: 5.4
作者:
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两种单纯疱疹病毒株之间的物理差异在氯化铯沉淀中明显可见。
DOI: 10.1016/0042-6822(61)90079-4
发表时间: 1961
期刊: Virology
影响因子: 3.7
作者:
B. Roizman;P. Roane
通讯作者: P. Roane