Complete genome sequence of the first bluetongue virus serotype 7 isolate from China: evidence for entry of African-lineage strains and reassortment between the introduced and native strains
Complete genome sequence of the first bluetongue virus serotype 7 isolate from China: evidence for entry of African-lineage strains and reassortment between the introduced and native strains
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中国第一个血清型 7 蓝舌病病毒分离株的完整基因组序列：非洲谱系毒株进入以及引进毒株与本土毒株重配的证据
DOI：
10.1007/s00705-015-2624-7
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发表时间：
2015-10
影响因子：
2.7
通讯作者：
Li Huachun
中科院分区：
文献类型：
--
作者：
Yang Heng;Lv Minna;Sun Minfei;Lin Liqin;Kou Meilin;Gao Lin;Liao Defang;Xiong Heli;He Yuwen;Li Huachun
蓝舌病毒(BTV)主要感染绵羊，但也可传播给其他家养和野生反刍动物，造成相当大的经济负担和贸易限制。我们对BTV的起源、运动和分布的理解一直受到以下事实的阻碍：这种病毒有一个分段的基因组，有可能重新分类，存在27个已识别的血清型，以及缺乏从世界不同地区分离的病毒的完整序列。BTV血清型7是亚洲流行的BTV血清型之一。然而，目前还没有这种血清型的亚洲分离株的完整基因组序列。为了了解中国地区牛瘟病毒感染的分子流行病学，我们首次报道了2014年在中国分离到的牛瘟病毒7型毒株GDST008的全基因组序列。该序列也代表了来自亚洲的BTV 7型的第一个完整基因组序列，也是世界上第三个。序列分析表明，GDST008由非洲系BTV病毒和中国BTV病毒的片段组成。总之，这些结果提高了我们对BTV的起源、出现/重新出现和移动的理解，从而可以应用于疫苗和诊断的开发。
Bluetongue virus (BTV) mainly infects sheep but can be transmitted to other domestic and wild ruminants, resulting in a considerable financial burden and trade restriction. Our understanding of the origin, movement, and distribution of BTV has been hindered by the fact that this virus has a segmented genome with the possibility of reassortment, the existence of 27 identified serotypes, and a lack of complete sequences of viruses isolated from different parts of the world. BTV serotype 7 is one of the prevalent BTV serotypes in Asia. Nonetheless, no complete genomic sequence of an Asian isolate of this serotype is available. In an effort to understand the molecular epidemiology of BTV infection in China, for the first time, we report here the complete genome sequence of a BTV serotype 7 strain, GDST008, which was isolated in 2014 in China. This sequence also represents the first complete genome sequence of a BTV serotype 7 from Asia and the third one in the world. Sequence analysis suggests that GDST008 consists of segments from BTV viruses of African lineage as well as those from China. Together, these results improve our understanding of the origin, emergence/re-emergence, and movement of BTV and thus can be applied in the development of vaccines and diagnostics.
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DOI：
10.1128/genomea.00045-15
发表时间：
2015-04-09
期刊：
Genome announcements
影响因子：
--
作者：
Maan S;Maan NS;Belaganahalli MN;Kumar A;Batra K;Rao PP;Hemadri D;Reddy YN;Putty K;Krishnajyothi Y;Reddy GH;Singh KP;Hegde NR;Nomikou K;Sreenivasulu D;Mertens PP
通讯作者：
Mertens PP
影响因子：
4.2
作者：
Kirkland, PD;Zhang, N;Hunt, NT
通讯作者：
Hunt, NT
影响因子：
5.4
作者：
SAMAL, SK;LIVINGSTON, CW;RAMIG, RF
通讯作者：
RAMIG, RF
影响因子：
3.8
作者：
Maan, S.;Maan, N. S.;Mertens, P. P. C.
通讯作者：
Mertens, P. P. C.
DOI：
10.1128/genomea.00016-15
发表时间：
2015-03-12
期刊：
Genome announcements
影响因子：
--
作者：
Jenckel M;Bréard E;Schulz C;Sailleau C;Viarouge C;Hoffmann B;Höper D;Beer M;Zientara S
通讯作者：
Zientara S