Comorbid Depressive and Anxiety Symptoms and Their Correlates Among 93,078 Multiethnic Adults in Southwest China.
Comorbid Depressive and Anxiety Symptoms and Their Correlates Among 93,078 Multiethnic Adults in Southwest China.
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DOI：
10.3389/fpubh.2021.783687
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发表时间：
2021
影响因子：
5.2
通讯作者：
Zhao X
中科院分区：
文献类型：
--
作者：
Liu Q;Wangqing P;Baima Y;Wang S;Shen Z;Zhou J;Song H;Liu Y;Liu X;Luo P;Zhao X
背景：抑郁症状和焦虑症状通常共存，严重增加了世界范围内的疾病负担。关于中国多民族人群中抑郁和焦虑共病症状的模式和相关性知之甚少。研究方法：这项基于人群的研究调查了93，078名年龄在30-79岁之间的参与者（37，193名男性，55，885名女性）的共病抑郁和焦虑症状与生活方式、压力性生活事件、慢性疾病以及身心健康的综合关联。中国西南地区七个民族。多变量logistic回归模型用于估计相关性。结果如下：总体而言，2.9%（男性2.1%，女性3.5%）的参与者患有抑郁和焦虑症状;多种族人群之间存在相当大的异质性。患有慢性疾病的参与者比没有慢性疾病的参与者更有可能患有合并症;风湿性心脏病患者报告的风险最高，比值比（OR）为6.25，95%置信区间（CI）为4.06-9.62。经历过3次或3次以上的压力性生活事件（OR，8.43，95%CI：7.27-9.77），自评健康状况极差（OR，33.60，95%CI：25.16-44.87），生活非常不满意（OR，33.30，95% CI：23.73-46.74）与抑郁症状和焦虑症状共病有较强的正相关性，且呈剂量-反应关系（P < 0.05）。高频率的体力活动有负相关。所有的关联都比单独的抑郁症状或焦虑症状更强。结论：我们的研究结果强调，需要把重点放在弱势群体与抑郁和焦虑症状共病，最终帮助早期预防和改善健康公平的欠发达和高度城市化地区。
Background: Depressive symptoms and anxiety symptoms commonly coexist and severely increases the disease burden worldwide. Little is known about the patterns and correlates of comorbid depressive and anxiety symptoms among the multiethnic populations of China. Methods: This population-based study investigated the comprehensive associations of comorbid depressive and anxiety symptoms with lifestyles, stressful life events, chronic diseases, and physical and mental well-being among 93,078 participants (37,193 men, 55,885 women) aged 30–79 years across seven ethnic groups in Southwest China. Multivariable logistic regression models were used to estimate associations. Results: Overall, 2.9% (2.1% in men and 3.5% in women) participants had comorbid depressive and anxiety symptoms; there was considerable heterogeneity among multiethnic populations. Participants with chronic diseases were more likely to have comorbidity than those without them; people with rheumatic heart disease reported the highest risk, with an odds ratio (OR) of 6.25 and 95% confidence interval (CI) of 4.06–9.62. Having experienced 3 or more stressful life events (OR, 8.43, 95% CI: 7.27–9.77), very poor self-rated health status (OR, 33.60, 95%CI: 25.16–44.87), and very unsatisfied life (OR, 33.30, 95% CI: 23.73–46.74) had strong positive associations with comorbid depressive symptoms and anxiety symptoms, with a dose-response relationship (P < 0.05). High frequency of physical activity had negative associations. All the associations were stronger than depressive symptoms alone or anxiety symptoms alone. Conclusions: Our findings emphasize the need to focus on the vulnerable ethnic groups with comorbid depressive and anxiety symptoms, ultimate for help early prevention and improvement of health equity in the underdevelopment and high urbanization areas.
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影响因子：
5.4
作者：
Chen, Juan;Chen, Shuo;Landry, Pierre F.
通讯作者：
Landry, Pierre F.
影响因子：
2.6
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Evans JJ
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通讯作者：
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影响因子：
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作者：
Lamers, Femke;van Oppen, Patricia;Penninx, Brenda W. J. H.
通讯作者：
Penninx, Brenda W. J. H.