Rat offspring's microbiota composition is predominantly shaped by the postnatal maternal diet rather than prenatal diet.
Rat offspring's microbiota composition is predominantly shaped by the postnatal maternal diet rather than prenatal diet.
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DOI:
10.1016/j.physbeh.2022.113987
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发表时间:
2023-01-01
影响因子:
2.9
通讯作者:
de La Serre, Claire B.
中科院分区:
文献类型:
--
作者:
Schade, Ruth;Song, Lin;Cordner, Zachary A.;Ding, Hua;Peterson, Daniel A.;Moran, Timothy H.;Tamashiro, Kellie L.;de La Serre, Claire B.
This study assessed the impact of maternal diet during pregnancy versus lactation on offspring gut microbiota. Sprague-Dawley dams were fed high fat (HF) or Chow diets during pregnancy, and their male offspring were raised by a different dam consuming the same or opposite diet (Chow-Chow, Chow-HF, HF-Chow, and HF-HF). Microbiota analysis showed that maternal lactation diet, rather than pregnancy diet, determined offspring microbiota profiles at weaning. Increased abundances of Turicibacter, Staphylococcus, and Ruminococcus were characteristic of chow lactation groups. Lactococcus, Streptococcus, and Parabacteroides were characteristic of HF lactation groups and positively correlated with offspring body weight.
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DOI:
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影响因子:
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