Biscuit consumption and diabetic retinopathy incidence in adults in the United States.
Biscuit consumption and diabetic retinopathy incidence in adults in the United States.
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DOI：
10.1186/s13098-022-00860-7
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发表时间：
2022-07-06
影响因子：
4.8
通讯作者：
中科院分区：
文献类型：
--
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食物对人体健康有相当大的影响，并直接关系到糖尿病患者的血糖控制。然而，人们对饼干对糖尿病视网膜病变的影响知之甚少，饼干是一些国家大量消费的传统食品。本研究旨在探讨饼干消费量与美国成年人糖尿病视网膜病变患病率之间的关系。这项以人群为基础的横断面研究包括了来自国家健康和营养检查调查数据库的1904名参与者。使用二元logistic回归模型评估不同饼干消费频率与糖尿病视网膜病变患病率之间的关系。进行趋势检验、分层分析和交互作用分析。在对性别、年龄、种族、教育程度、婚姻状况、家庭贫困收入比、吸烟饮酒习惯、空腹血糖水平、血红蛋白A1c水平、糖尿病诊断、胰岛素使用、血压、体重指数等可能混杂因素进行调整后，每年1 ~ 11次、每月1 ~ 3次、每周1次以上食用饼干者的患病率分别为139.8%（95%可信区间1.003 ~ 5.734）、182.1%（95%可信区间1.106 ~ 7.191）、与从不吃饼干的人相比，糖尿病视网膜病变患病率分别高出236.2%（95%可信区间，1.335-9.844）。对于男性、非西班牙裔和超重（体重指数≥25 kg/m2）亚组，趋势检验表明，糖尿病视网膜病变患病率随着饼干食用频率的增加而显著升高（P趋势分别为0.021、0.009和0.002）。交互作用分析表明，上述混杂因素在饼干消费量与糖尿病视网膜病变患病率之间的关系中没有交互作用。糖尿病视网膜病变的风险与饼干的摄入量呈正相关。此外，对于男性、非西班牙裔或超重个体，糖尿病视网膜病变的风险随着饼干食用频率的增加而显著增加。在线版本包含补充材料，可在10.1186/s13098-022-00860-7获得。
Foods have a considerable influence on human health and were directly related to glycemic control for diabetes patients. However, little is known about the effects of biscuits, a traditional food consumed in large amounts in several countries, on diabetic retinopathy. This study aimed to explore the association between biscuit consumption and diabetic retinopathy prevalence in adults of the United States population. A cross-sectional study with 1904 participants from the National Health and Nutrition Examination Survey database were included in this population-based, cross-sectional study. The association between different consumption frequencies of biscuit and diabetic retinopathy prevalence was evaluated using a binary logistic regression model. Trend test, stratified and interaction analyses were also performed. After possible confounders including sex, age, ethnicity, education, marital status, family poverty income ratio, smoking and alcohol consumption habit, fasting blood glucose level, hemoglobin A1c level, diagnosis of diabetes, insulin use, blood pressure, body mass index were adjusted, the participants who consumed biscuit 1–11 times a year, 1–3 times a month, and more than once a week had a 139.8% (95% confidence interval, 1.003–5.734), 182.1% (95% confidence interval, 1.106–7.191), and 236.2% (95% confidence interval, 1.335–9.844) higher risk of diabetic retinopathy prevalence, respectively, compared with those who never ate biscuit. For male, non-Hispanic, and overweight (body mass index ≥ 25 kg/m2) subgroups, the trend test demonstrated that the diabetic retinopathy prevalence significantly elevated with increased frequency of biscuit consumption (P trend = 0.021, 0.009, and 0.002, respectively). The interaction analysis suggested that no aforementioned confounders played an interactive role in the relationship between biscuit consumption and diabetic retinopathy prevalence. The risk of diabetic retinopathy was positively associated with biscuit consumption. Moreover, for male, non-Hispanic, or overweight individuals, the risk of diabetic retinopathy significantly increased with the frequency of biscuit consumption. The online version contains supplementary material available at 10.1186/s13098-022-00860-7.
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影响因子：
158.5
作者：
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