Epidemiology of hip fracture: Worldwide geographic variation.

Epidemiology of hip fracture: Worldwide geographic variation.
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髋部骨折的流行病学:全球地理变化。

DOI:
10.4103/0019-5413.73656
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发表时间:
2011-01
影响因子:
1
通讯作者:
Cooper C
Cooper C
中科院分区:
医学4区
文献类型:
--
作者:
Dhanwal DK;Dennison EM;Harvey NC;Cooper C

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骨质疏松症是一个主要的健康问题,尤其是在老年人群中,并且与髋部、脊柱和手腕的脆性骨折有关。髋部骨折会导致老年人的发病率和死亡率。世界人口结构将发生变化,越来越多的老年人生活在发展中国家,据估计,到 2050 年,一半的髋部骨折将发生在亚洲。这篇使用 PubMed 数据库进行的综述描述了世界不同地区髋部骨折的发生率,并讨论了这种广泛地理差异的可能原因。对不同研究数据的分析显示,世界各地存在广泛的地理差异,工业化国家报告的髋部骨折发生率高于发展中国家。髋部骨折发生率最高的是北欧和美国,最低的是拉丁美洲和非洲。科威特、伊朗、中国和香港等亚洲国家的髋部骨折发生率中等。欧洲的研究也发现了南北梯度,美国北部的裂缝比南部多。造成这种差异的因素是人口统计特征(发病率较高的国家生活着更多的老年人)以及种族、纬度和环境因素的影响。了解这种不断变化的地理差异将有助于政策制定者制定战略,减轻印度等发展中国家髋部骨折的负担,印度将在未来几十年内首当其冲地面临这一问题。
Osteoporosis is a major health problem, especially in elderly populations, and is associated with fragility fractures at the hip, spine, and wrist. Hip fracture contributes to both morbidity and mortality in the elderly. The demographics of world populations are set to change, with more elderly living in developing countries, and it has been estimated that by 2050 half of hip fractures will occur in Asia. This review conducted using the PubMed database describes the incidence of hip fracture in different regions of the world and discusses the possible causes of this wide geographic variation. The analysis of data from different studies show a wide geographic variation across the world, with higher hip fracture incidence reported from industrialized countries as compared to developing countries. The highest hip fracture rates are seen in North Europe and the US and lowest in Latin America and Africa. Asian countries such as Kuwait, Iran, China, and Hong Kong show intermediate hip fracture rates. There is also a north–south gradient seen in European studies, and more fractures are seen in the north of the US than in the south. The factors responsible of this variation are population demographics (with more elderly living in countries with higher incidence rates) and the influence of ethnicity, latitude, and environmental factors. The understanding of this changing geographic variation will help policy makers to develop strategies to reduce the burden of hip fractures in developing countries such as India, which will face the brunt of this problem over the coming decades.
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