Novel human rhinoviruses and exacerbation of asthma in children.

Novel human rhinoviruses and exacerbation of asthma in children.
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DOI:
10.3201/eid1411.080386
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发表时间:
2008-11
影响因子:
11.8
通讯作者:
Erdman DD
Erdman DD
中科院分区:
医学2区
文献类型:
--
作者:
Khetsuriani N;Lu X;Teague WG;Kazerouni N;Anderson LJ;Erdman DD

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为了确定人鼻病毒(HRV)和哮喘之间的联系,我们使用了2003年3月至2004年2月在哮喘儿童中进行的病例对照研究的数据。分子特征鉴定了几种可能的新HRV,并显示与哮喘急性发作的相关性主要由HRV-A和8种毒株(基因组C)的遗传学上不同的进化枝驱动。
To determine links between human rhinoviruses (HRV) and asthma, we used data from a case–control study, March 2003–February 2004, among children with asthma. Molecular characterization identified several likely new HRVs and showed that association with asthma exacerbations was largely driven by HRV-A and a phylogenetically distinct clade of 8 strains, genogroup C.
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