Higher 24-h respiratory quotient and higher spontaneous physical activity in nighttime eaters.

Higher 24-h respiratory quotient and higher spontaneous physical activity in nighttime eaters.
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在夜间食者中,较高的24小时呼吸商和较高的自发体育锻炼。

DOI:
10.1038/oby.2010.206
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发表时间:
2011-03
期刊:
Obesity (Silver Spring, Md.)
影响因子:
--
通讯作者:
Krakoff J
Krakoff J
中科院分区:
其他
文献类型:
--
作者:
Gluck ME;Venti CA;Salbe AD;Votruba SB;Krakoff J

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我们之前已经表明,较高的24小时呼吸商(24小时RQ)预测更大的随意食物摄入量,夜间进食者(NE)在住院患者食物摄入量研究中摄入更多的卡路里,并随着时间的推移增加更多的体重。我们调查了24小时RQ是否在表现出夜间进食行为的个体中更高。健康非糖尿病皮马印第安人(PI; n = 97,54名男性/43名女性)和白人(W; n = 32,22名男性/10名女性)入住我们的临床研究单位。经过3天的体重维持饮食,24小时能量消耗(24小时EE),24小时RQ,碳水化合物(CHOX)和脂质氧化(LIPOX)的速率,和自发的体力活动(SPA),而志愿者在能量平衡,不能消耗多余的热量代谢室进行了测量。个体随后从计算机化自动售货机随意进食3天,并记录食物摄入的量和时间。55个人(36%; 39 PI,16 W)是NE,他们在自动售货机上的3天中至少有一天在上午11点到凌晨5点之间进食。NE和非NE之间的BMI或体脂百分比没有差异。在调整了年龄、性别、种族、去脂质量、脂肪质量和能量平衡后,与非NE相比,NE具有较高的24小时RQ(P = 0.01)、较高的CHOX(P = 0.009)、较低的LIPOX(P = 0.03)和较高的24小时SPA(P = 0.04)。两组间校正后的24小时EE或睡眠RQ无差异。具有夜间进食行为的个体具有较高的24小时RQ,较高的CHOX和较低的LIPOX,这是一种与食物摄入量增加和体重增加相关的表型。
We have previously shown that a higher 24-h respiratory quotient (24-h RQ) predicts greater ad-libitum food intake and that nighttime eaters (NE) ingested more calories during an in-patient food intake study and gained more weight over time. We investigated whether 24-h RQ was higher in individuals who exhibited nighttime eating behavior. Healthy nondiabetic Pima Indians (PI; n = 97, 54 male/43 female) and whites (W; n = 32, 22 male/10 female) were admitted to our Clinical Research Unit. After 3 days of a weight maintaining diet, 24-h energy expenditure (24-h EE), 24-h RQ, rates of carbohydrate (CHOX) and lipid oxidation (LIPOX), and spontaneous physical activity (SPA) were measured in a metabolic chamber whereas volunteers were in energy balance and unable to consume excess calories. Individuals subsequently ate ad libitum from a computerized vending machine for 3 days with amount and timing of food intake recorded. Fifty-five individuals (36%; 39 PI, 16 W) were NE, who ate between 11 am and 5 am on at least one of the 3 days on the vending machines. There were no differences in BMI or percentage body fat between NE and non-NE. After adjusting for age, sex, race, fat-free mass, fat mass, and energy balance, NE had a higher 24-h RQ (P = 0.01), higher CHOX (P = 0.009), and lower LIPOX (P = 0.03) and higher 24-h SPA (P = 0.04) compared to non-NE. There were no differences in adjusted 24-h EE or sleep RQ between the groups. Individuals with nighttime eating behavior have higher 24-h RQ, higher CHOX and lower LIPOX, a phenotype associated with increased food intake and weight gain.
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发表时间: 2003-07-01
影响因子: 3.1
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