Development of Korean standard brain templates.
Development of Korean standard brain templates.
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DOI：
10.3346/jkms.2005.20.3.483
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发表时间：
2005-06
影响因子：
4.5
通讯作者：
Lee MC
中科院分区：
文献类型：
--
作者：
Lee JS;Lee DS;Kim J;Kim YK;Kang E;Kang H;Kang KW;Lee JM;Kim JJ;Park HJ;Kwon JS;Kim SI;Yoo TW;Chang KH;Lee MC
我们开发了基于韩国正常志愿者的MR和正电子发射断层扫描(PET)图像的年龄、性别和种族特定的脑模板。78名正常右利手志愿者(男/女=49/29)接受了3DT1加权SPGR、MR和F-18FDGPET扫描。对于标准模板的生成，为每个性别选择了一个具有平均半球形状的最佳目标大脑。然后通过对目标大脑的线性变换对MR图像进行空间归一化，并将归一化参数重新应用于PET图像。研究对象按性别分为两组：青年/中年(55岁)组和老年组。通过对空间归一化图像进行平均来构建青年和老年MRI/PET模板。韩国人的模板显示出不同的形状和大小(男性的平均长、宽和高分别为16.5、14.3和12.1厘米，女性的平均长、宽和高分别为15.6、13.5和11.4厘米)，而高加索人的模板为18.3、14.2和13.3厘米。本研究开发的MRI和PET模板将为更准确的立体定向标准化和解剖定位提供框架。
We developed age, gender and ethnic specific brain templates based on MR and Positron-Emission Tomography (PET) images of Korean normal volunteers. Seventy-eight normal right-handed volunteers (M/F=49/29) underwent 3D T1-weighted SPGR MR and F-18-FDG PET scans. For the generation of standard templates, an optimal target brain that has the average global hemispheric shape was selected for each gender. MR images were then spatially normalized by linear transformation to the target brains, and normalization parameters were reapplied to PET images. Subjects were subdivided into 2 groups for each gender: the young/midlife (<55 yr) and the elderly groups. Young and elderly MRI/PET templates were composed by averaging the spatially normalized images. Korean templates showed different shapes and sizes (mean length, width, and height of the brains were 16.5, 14.3 and 12.1 cm for man, and 15.6, 13.5 and 11.4 cm for woman) from the template based on Caucasian (18.3, 14.2, and 13.3 cm). MRI and PET templates developed in this study will provide the framework for more accurate stereotactic standardization and anatomical localization.
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影响因子：
3.8
作者：
Yoon, U;Lee, JM;Kim, SI
通讯作者：
Kim, SI
影响因子：
1.3
作者：
FOX, PT;PERLMUTTER, JS;RAICHLE, ME
通讯作者：
RAICHLE, ME
影响因子：
1.6
作者：
Giraud, AL;Truy, E;Frackowiak, R
通讯作者：
Frackowiak, R
影响因子：
64.8
作者：
Lee, DS;Lee, JS;Kim, CS
通讯作者：
Kim, CS
影响因子：
5.7
作者：
Kochunov, P;Lancaster, J;Fox, P
通讯作者：
Fox, P