Alterations of Cerebral Hemodynamics and Network Properties Induced by Newsvendor Problem in the Human Prefrontal Cortex.
Alterations of Cerebral Hemodynamics and Network Properties Induced by Newsvendor Problem in the Human Prefrontal Cortex.
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DOI：
10.3389/fnhum.2020.598502
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发表时间：
2020
影响因子：
2.9
通讯作者：
Liu H
中科院分区：
文献类型：
--
作者：
Wanniarachchi H;Lang Y;Wang X;Pruitt T;Nerur S;Chen KY;Liu H
虽然许多出版物已经报道了在各种风险条件下决策的脑血流动力学反应，但没有库存管理场景，如报童问题（NP），已经与神经影像学一起研究。在这项研究中，我们假设（I）NP刺激背外侧前额叶皮层（DLPFC）和眶额皮层（OFC）与额叶极区（FPA）显着在人类大脑中，和（II）当一个人从休息过渡到NP决策阶段时，局部脑网络属性增加。采用77通道宽视场功能近红外光谱（fNIRS）系统，对27名健康人进行了NP对额叶脑血流动力学的影响。使用一般线性模型（GLM）和图论分析（GTA）研究了NP诱导的氧合血红蛋白浓度变化Δ[HbO]。在所有受试者中，在DLPFC和OFC+FPA中均显示出NP诱导的显著激活。具体而言，高风险NP与低利润率（LM）激活左DLPFC，但失活右DLPFC在14个科目，而低风险NP与高利润率（HM）刺激DLPFC和OFC+FPA在13个科目。在NP决策下，网络度量的局部效率、聚类系数和路径长度都有显著提高。总之，多通道fNIRS使我们能够识别DLPFC和OFC+FPA作为受试者在进行库存管理风险决策时大脑激活的关键皮层区域。我们证明，挑战性的NP导致右DLPFC内的失活，由于更高水平的应力。此外，当一个人从休息阶段过渡到NP决策阶段时，局部大脑网络特性会增加。
While many publications have reported brain hemodynamic responses to decision-making under various conditions of risk, no inventory management scenarios, such as the newsvendor problem (NP), have been investigated in conjunction with neuroimaging. In this study, we hypothesized (I) that NP stimulates the dorsolateral prefrontal cortex (DLPFC) and the orbitofrontal cortex (OFC) joined with frontal polar area (FPA) significantly in the human brain, and (II) that local brain network properties are increased when a person transits from rest to the NP decision-making phase. A 77-channel functional near infrared spectroscopy (fNIRS) system with wide field-of-view (FOV) was employed to measure frontal cerebral hemodynamics in response to NP in 27 healthy human subjects. NP-induced changes in oxy-hemoglobin concentration, Δ[HbO], were investigated using a general linear model (GLM) and graph theory analysis (GTA). Significant activation induced by NP was shown in both DLPFC and OFC+FPA across all subjects. Specifically, higher risk NP with low-profit margins (LM) activated left-DLPFC but deactivated right-DLPFC in 14 subjects, while lower risk NP with high-profit margins (HM) stimulated both DLPFC and OFC+FPA in 13 subjects. The local efficiency, clustering coefficient, and path length of the network metrics were significantly enhanced under NP decision making. In summary, multi-channel fNIRS enabled us to identify DLPFC and OFC+FPA as key cortical regions of brain activations when subjects were making inventory-management risk decisions. We demonstrated that challenging NP resulted in the deactivation within right-DLPFC due to higher levels of stress. Also, local brain network properties were increased when a person transitioned from the rest phase to the NP decision-making phase.
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影响因子：
5.3
作者：
Achard, S;Salvador, R;Bullmore, ET
通讯作者：
Bullmore, ET
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作者：
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作者：
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影响因子：
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作者：
Cai L;Dong Q;Niu H
通讯作者：
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