Examining Optimism, Psychosocial Risks, and Cardiovascular Health Using Life's Simple 7 Metrics in the Multi-Ethnic Study of Atherosclerosis and the Jackson Heart Study.
Examining Optimism, Psychosocial Risks, and Cardiovascular Health Using Life's Simple 7 Metrics in the Multi-Ethnic Study of Atherosclerosis and the Jackson Heart Study.
复制标题
DOI：
10.3389/fcvm.2021.788194
复制
发表时间：
2021
影响因子：
3.6
通讯作者：
Howe CJ
中科院分区：
文献类型：
--
作者：
Park JW;Dulin AJ;Needham BL;Sims M;Loucks EB;Fava JL;Dionne LA;Scarpaci MM;Eaton CB;Howe CJ
研究背景：乐观与更好的心血管健康（CVH）呈正相关。然而，缺乏前瞻性研究表明乐观对CVH的好处，特别是在逆境中，即，心理社会风险本研究探讨了乐观和CVH结果之间的前瞻性关系的基础上，生活的简单7（LS 7）指标和多层次的心理社会风险是否修改上述关系。研究方法：我们使用来自两个美国队列的协调数据检查了自我报告的乐观和CVH：多种族动脉粥样硬化研究（梅萨）和杰克逊心脏研究（JHS）。使用改良的泊松回归模型，在梅萨参与者（N = 3，520）中使用LS 7估计乐观与CVH之间的关系，并在JHS和梅萨参与者（N = 5，541）中检查基于四个生物LS 7指标（体重指数，血压，胆固醇和血糖）的关系。对于所有CVH结局，我们评估了心理社会风险的效应测量修正。结果如下：在梅萨参与者中，使用LS 7比较报告高度或中度乐观的参与者与乐观水平最低的参与者，理想或中度CVH的调整后风险比（aRR）分别为1.10 [95%置信区间（CI）：1.04-1.16]和1.05（95% CI：0.99-1.11）。在梅萨和JHS参与者中，基于四个生物学LS 7指标的所有理想或中间（与没有差）指标的相应aRR分别为1.05（0.98-1.12）和1.04（0.97-1.11）。基于四个生物学LS 7指标，具有较低心血管风险（0-1差指标）的相应aRR分别为1.01（0.98-1.03）和1.01（0.98-1.03）。有一些证据表明，基于四个生物LS 7指标，LS 7结果的邻居剥夺和理想或中间（没有差）指标结果的慢性应激对效果有影响。结论：我们的研究结果表明，更大的乐观情绪与更好的CVH正相关的基础上，在种族/民族多样化的研究人群中的某些LS 7的结果。这种关系可能是由特定的心理社会风险的影响措施修改。乐观主义显示，作为CVH干预的潜在领域，前景进一步看好。然而，还需要额外的前瞻性和干预研究。
Background: Optimism has been shown to be positively associated with better cardiovascular health (CVH). However, there is a dearth of prospective studies showing the benefits of optimism on CVH, especially in the presence of adversities, i.e., psychosocial risks. This study examines the prospective relationship between optimism and CVH outcomes based on the Life's Simple 7 (LS7) metrics and whether multilevel psychosocial risks modify the aforementioned relationship. Methods: We examined self-reported optimism and CVH using harmonized data from two U.S. cohorts: Multi-Ethnic Study of Atherosclerosis (MESA) and Jackson Heart Study (JHS). Modified Poisson regression models were used to estimate the relationship between optimism and CVH using LS7 among MESA participants (N = 3,520) and to examine the relationship of interest based on four biological LS7 metrics (body mass index, blood pressure, cholesterol, and blood glucose) among JHS and MESA participants (N = 5,541). For all CVH outcomes, we assessed for effect measure modification by psychosocial risk. Results: Among MESA participants, the adjusted risk ratio (aRR) for ideal or intermediate CVH using LS7 comparing participants who reported high or medium optimism to those with the lowest level of optimism was 1.10 [95% Confidence Interval (CI): 1.04–1.16] and 1.05 (95% CI: 0.99–1.11), respectively. Among MESA and JHS participants, the corresponding aRRs for having all ideal or intermediate (vs. no poor) metrics based on the four biological LS7 metrics were 1.05 (0.98–1.12) and 1.04 (0.97–1.11), respectively. The corresponding aRRs for having lower cardiovascular risk (0–1 poor metrics) based on the four biological LS7 metrics were 1.01 (0.98–1.03) and 1.01 (0.98–1.03), respectively. There was some evidence of effect modification by neighborhood deprivation for the LS7 outcome and by chronic stress for the ideal or intermediate (no poor) metrics outcome based on the four biological LS7 metrics. Conclusion: Our findings suggest that greater optimism is positively associated with better CVH based on certain LS7 outcomes among a racially/ethnically diverse study population. This relationship may be effect measure modified by specific psychosocial risks. Optimism shows further promise as a potential area for intervention on CVH. However, additional prospective and intervention studies are needed.
登录
查看更多内容
影响因子：
37.8
作者：
Churchwell, Keith;Elkind, Mitchell S. V.;Williams, Olajide
通讯作者：
Williams, Olajide
影响因子：
1.9
作者：
Boehm, Julia K.;Vie, Loryana L.;Kubzansky, Laura D.
通讯作者：
Kubzansky, Laura D.
影响因子：
3.7
作者：
Carrillo, Alba;Martinez-Sanchis, Marian;Banos, Rosa M.
通讯作者：
Banos, Rosa M.
影响因子：
3.5
作者：
Fang, Na;Jiang, Menglin;Fan, Yu
通讯作者：
Fan, Yu
影响因子：
12.8
作者：
Carver, Charles S.;Scheier, Michael F.;Segerstrom, Suzanne C.
通讯作者：
Segerstrom, Suzanne C.