Neural correlates of socioeconomic status in the developing human brain.
Neural correlates of socioeconomic status in the developing human brain.
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DOI：
10.1111/j.1467-7687.2012.01147.x
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发表时间：
2012-07
影响因子：
3.7
通讯作者：
Sowell ER
中科院分区：
文献类型：
--
作者：
Noble KG;Houston SM;Kan E;Sowell ER
童年时期的社会经济差异与大脑发生巨大变化期间认知和社会情感发展的显着差异有关。然而，社会经济地位（SES）塑造发展的神经生物学途径仍然知之甚少。行为证据表明，语言，记忆，社会情绪处理和认知控制在SES中表现出相对较大的差异。在这里，我们调查了是否可以观察到的SES在几个神经区域，支持这些技能的体积差异。在一个样本的60个社会经济上不同的儿童，高度显着的SES差异，在海马和杏仁核的区域脑容量观察。此外，在左侧上级颞回和左侧额下回中观察到SES ×年龄的交互作用，表明这些区域的SES差异随着年龄的增加而增加。这些结果不能用性别、种族或智商的差异来解释。可能的机制包括家庭语言环境的差异和压力暴露，这可能是在神经可塑性高的时候进行干预的目标。
Socioeconomic disparities in childhood are associated with remarkable differences in cognitive and socio-emotional development during a time when dramatic changes are occurring in the brain. Yet, the neurobiological pathways through which socioeconomic status (SES) shapes development remain poorly understood. Behavioral evidence suggests that language, memory, social-emotional processing, and cognitive control exhibit relatively large differences across SES. Here we investigated whether volumetric differences could be observed across SES in several neural regions that support these skills. In a sample of 60 socioeconomically diverse children, highly significant SES differences in regional brain volume were observed in the hippocampus and the amygdala. In addition, SES × age interactions were observed in the left superior temporal gyrus and left inferior frontal gyrus, suggesting increasing SES differences with age in these regions. These results were not explained by differences in gender, race or IQ. Likely mechanisms include differences in the home linguistic environment and exposure to stress, which may serve as targets for intervention at a time of high neural plasticity.
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DOI：
10.1073/pnas.0606302103
发表时间：
2006-09-19
影响因子：
11.1
作者：
Dehaene-Lambertz, Ghislaine;Hertz-Pannier, Lucie;Dehaene, Stanislas
通讯作者：
Dehaene, Stanislas
影响因子：
4.2
作者：
Gianaros, Peter J.;Horenstein, Jeffrey A.;Cohen, Sheldon
通讯作者：
Cohen, Sheldon
影响因子：
4.6
作者：
Eckert, MA;Lombardino, LJ;Leonard, CM
通讯作者：
Leonard, CM
影响因子：
4.6
作者：
Bradley, RH;Corwyn, RF;Coll, CG
通讯作者：
Coll, CG
影响因子：
4.2
作者：
Gianaros, Peter J;Horenstein, Jeffrey A;Cohen, Sheldon;Matthews, Karen A;Brown, Sarah M;Flory, Janine D;Critchley, Hugo D;Manuck, Stephen B;Hariri, Ahmad R
通讯作者：
Hariri, Ahmad R