A cerebellar mechanism for learning prior distributions of time intervals.
A cerebellar mechanism for learning prior distributions of time intervals.
复制标题
DOI:
10.1038/s41467-017-02516-x
复制
发表时间:
2018-02-01
影响因子:
16.6
通讯作者:
Jazayeri M
中科院分区:
文献类型:
--
作者:
Narain D;Remington ED;Zeeuw CI;Jazayeri M
Knowledge about the statistical regularities of the world is essential for cognitive and sensorimotor function. In the domain of timing, prior statistics are crucial for optimal prediction, adaptation and planning. Where and how the nervous system encodes temporal statistics is, however, not known. Based on physiological and anatomical evidence for cerebellar learning, we develop a computational model that demonstrates how the cerebellum could learn prior distributions of time intervals and support Bayesian temporal estimation. The model shows that salient features observed in human Bayesian time interval estimates can be readily captured by learning in the cerebellar cortex and circuit level computations in the cerebellar deep nuclei. We test human behavior in two cerebellar timing tasks and find prior-dependent biases in timing that are consistent with the predictions of the cerebellar model. Human timing behavior is biased towards previously encountered intervals and is predicted by Bayesian models. Here, the authors develop a computational model based in properties of the cerebellum to show how we might encode time estimates based on prior experience.
登录
查看更多内容
影响因子:
5.7
作者:
Brody CD;Hanks TD
通讯作者:
Hanks TD
影响因子:
4.3
作者:
Acerbi L;Wolpert DM;Vijayakumar S
通讯作者:
Vijayakumar S
影响因子:
64.8
作者:
Herzfeld DJ;Kojima Y;Soetedjo R;Shadmehr R
通讯作者:
Shadmehr R
影响因子:
5.3
作者:
Heiney, Shane A.;Kim, Jinsook;Medina, Javier F.
通讯作者:
Medina, Javier F.
影响因子:
1.9
作者:
FUJITA, M
通讯作者:
FUJITA, M