Application of Fourier transform-second-harmonic generation imaging to the rat cervix.
Application of Fourier transform-second-harmonic generation imaging to the rat cervix.
复制标题
DOI:
10.1111/jmi.12046
复制
发表时间:
2013-07
影响因子:
2
通讯作者:
Toussaint KC Jr
中科院分区:
文献类型:
--
作者:
Lau TY;Sangha HK;Chien EK;McFarlin BL;Wagoner Johnson AJ;Toussaint KC Jr
We present the application of Fourier transform-second-harmonic generation (FT-SHG) imaging to evaluate the arrangement of collagen fibers in five non-pregnant rat cervices. Tissue slices from the mid-cervix and near the external orifice of the cervix were analyzed in both two-dimensions (2D) and three-dimensions (3D). We validate that the cervical microstructure can be quantitatively assessed in three dimensions using FT-SHG imaging, and observe collagen fibers oriented both in and out-of-plane in the outermost and the innermost layers, which cannot be observed using 2D FT-SHG analysis alone. This approach has the potential to be a noninvasive method for measuring progressive changes in collagen organization during cervical remodeling in humans.
登录
查看更多内容
影响因子:
3.4
作者:
House M;Kaplan DL;Socrate S
通讯作者:
Socrate S
影响因子:
3.8
作者:
Rao, Raghu Ambekar Ramachandra;Mehta, Monal R.;Toussaint, Kimani C., Jr.
通讯作者:
Toussaint, Kimani C., Jr.
影响因子:
9.7
作者:
Myers, K. M.;Paskaleva, A. P.;Socrate, S.
通讯作者:
Socrate, S.
影响因子:
3.4
作者:
Campagnola, PJ;Millard, AC;Mohler, WA
通讯作者:
Mohler, WA
影响因子:
2.5
作者:
Pena, Ana-Maria;Fabre, Aurelie;Schanne-Klein, Marie-Claire
通讯作者:
Schanne-Klein, Marie-Claire