Preterm-associated visual impairment and estimates of retinopathy of prematurity at regional and global levels for 2010.
Preterm-associated visual impairment and estimates of retinopathy of prematurity at regional and global levels for 2010.
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DOI：
10.1038/pr.2013.205
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发表时间：
2013-12
影响因子：
3.6
通讯作者：
Gilbert, Clare
中科院分区：
文献类型：
--
作者：
Blencowe, Hannah;Lawn, Joy E.;Vazquez, Thomas;Fielder, Alistair;Gilbert, Clare
早产儿视网膜病变（ROP）是世界范围内可能可避免的儿童失明的主要原因。我们估计了全球和区域层面的ROP负担，为筛查和治疗方案、研究和数据优先级提供信息。通过系统回顾和荟萃分析，通过新生儿护理水平、ROP筛查和治疗的可及性来估计存活早产儿发生ROP和随后视力损害的风险。采用区室模型估计ROP病例和视障幸存者人数。2010年，估计有184,700（不确定范围：169,600-214,500）名早产儿出现任何阶段的ROP，其中20,000（15,500-27,200）名早产儿因ROP失明或严重视力受损，另有12,300（8,300-18,400）名早产儿出现轻度/中度视力障碍。65%的ROP视障患者出生在中等收入地区；6.2%（4.3-8.9%）的ROP视障婴儿出生在妊娠60 - 32周。与早产相关的其他条件造成的视力损害将影响更多的幸存者。在所有设施环境中改善对早产儿的护理，包括输氧和监测，将减少受ROP影响的婴儿数量。迫切需要改进数据跟踪和适合当地的筛查/治疗方案的覆盖范围。
Retinopathy of prematurity (ROP) is a leading cause of potentially avoidable childhood blindness worldwide. We estimated ROP burden at the global and regional levels to inform screening and treatment programs, research, and data priorities. Systematic reviews and meta-analyses were undertaken to estimate the risk of ROP and subsequent visual impairment for surviving preterm babies by level of neonatal care, access to ROP screening, and treatment. A compartmental model was used to estimate ROP cases and numbers of visually impaired survivors. In 2010, an estimated 184,700 (uncertainty range: 169,600–214,500) preterm babies developed any stage of ROP, 20,000 (15,500–27,200) of whom became blind or severely visually impaired from ROP, and a further 12,300 (8,300–18,400) developed mild/moderate visual impairment. Sixty-five percent of those visually impaired from ROP were born in middle-income regions; 6.2% (4.3–8.9%) of all ROP visually impaired infants were born at >32-wk gestation. Visual impairment from other conditions associated with preterm birth will affect larger numbers of survivors. Improved care, including oxygen delivery and monitoring, for preterm babies in all facility settings would reduce the number of babies affected with ROP. Improved data tracking and coverage of locally adapted screening/treatment programs are urgently required.
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DOI：
10.1111/j.1469-8749.1994.tb11853.x
发表时间：
1994-04-01
影响因子：
3.8
作者：
GILBERT, CE;CANOVAS, R;FOSTER, A
通讯作者：
FOSTER, A
影响因子：
2.1
作者：
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通讯作者：
Quiroga, Ana M.
影响因子：
8
作者：
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通讯作者：
Good, WV
影响因子：
8
作者：
Gilbert, C;Fielder, A;Zin, A
通讯作者：
Zin, A
影响因子：
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作者：
Austeng, Dordi;Kallen, Karin B. M.;Holmstrom, Gerd E.
通讯作者：
Holmstrom, Gerd E.