Non-Convulsive Status Epilepticus in the Presence of Catatonia: A Clinically Focused Review.

Non-Convulsive Status Epilepticus in the Presence of Catatonia: A Clinically Focused Review.
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DOI:
10.1016/j.genhosppsych.2020.11.008
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发表时间:
2021-01
影响因子:
7
通讯作者:
Kruse JL
Kruse JL
中科院分区:
医学2区
文献类型:
--
作者:
Volle DC;Marder KG;McKeon A;Brooks JO;Kruse JL

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紧张症通常与精神疾病有关,但也可能发生在医学和神经疾病中。癫痫持续状态(SE)是指持续5分钟以上的癫痫发作或5分钟内两次或两次以上的癫痫发作,但没有意识的间歇恢复。非惊厥性癫痫持续状态(NCSE)是一种没有明显运动活动的癫痫,可能存在紧张性症状。NCSE作为紧张症的潜在病因的相关性在文献中尚不清楚。我们对以紧张症为表现的NCSE的文献进行了系统的评价。检索PubMed和PsycInfo数据库,并对存在紧张症和NCSE的文章进行审查。15篇文章描述了27例符合纳入标准的病例。作者在文献中增加了1例。在NCSE中最常见的紧张性症状是沉默和麻木。以紧张症为表现的NCSE常见的临床特征包括新的紧张症症状、年龄超过50岁、共病的神经系统疾病或影响癫痫发作阈值的药物改变。有记录的精神病史也很常见,可能导致诊断延迟。在新的紧张性症状的鉴别诊断中考虑NCSE是很重要的。提供了一种建议的诊断评估方法。
Catatonia is classically associated with psychiatric conditions but may occur in medical and neurologic disorders. Status epilepticus (SE) is a seizure lasting more than five minutes or two or more seizures within a five-minute period without interictal recovery of consciousness. Non-convulsive status epilepticus (NCSE) is SE without prominent motor activity that may present with catatonic symptoms. The relevance of NCSE as a potential etiology for catatonia is not clear in the literature. A systematic review was completed to evaluate the literature on NCSE presenting with catatonia. PubMed and PsycInfo databases were searched and articles were reviewed for the presence of catatonia and NCSE. 15 articles describing 27 cases meeting inclusion criteria were identified. The authors add 1 case to the literature. The most common catatonic symptoms identified in NCSE were mutism and stupor. Clinical features frequent in NCSE presenting with catatonia included new catatonic symptoms, age over 50 years, comorbid neurological conditions, or a change in medications that affect seizure threshold. A documented psychiatric history was also common and may contribute to delayed diagnosis. It is important to consider NCSE in the differential diagnosis of new catatonic symptoms. A suggested approach to diagnostic evaluation is provided.
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